SCHEMBL7640575

SCHEMBL7640575

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Zr](F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA9 Q16790 3/20 0.33
ALDH1A1 P00352 3/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
CYP2A6 P11509 1/20 0.33
DHFR P00374 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
KDM4E B2RXH2 3/20 0.32
HPGD P15428 2/20 0.32
MAPT P10636 2/20 0.32
TDP2 O95551 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP3 P42574 1/20 0.32
HTT P42858 1/20 0.32
GALK1 P51570 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7639241 0.91 CA12 (0.33) CA12CA1CA2CA9ALDH1A1
SCHEMBL28266415 0.87 ALDH1A1 (0.34) CA12CA1CA2CA9ALDH1A1
SCHEMBL2525070 0.86 CA12 (0.33) CA12CA1CA2CA9ALDH1A1
SCHEMBL7602794 0.83 CA12 (0.32) CA12CA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL7629330 0.83 CA12 (0.32) CA12CA1CA2CA9ALDH1A1
SCHEMBL7601460 0.82 CA12 (0.32) CA12CA1CA2CA9ALDH1A1
Ethane SCHEMBL8631691 0.82 ALDH1A1 (0.33) CA12CA1CA2CA9ALDH1A1
SCHEMBL8573143 0.81 KDM1A (0.31) CA12CA1CA2CA9ALDH1A1
SCHEMBL7629329 0.81 NPC1 (0.33) CA12CA1CA2CA9ALDH1A1
SCHEMBL21980377 0.81 CA12 (0.31) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020143125-A1 Catalyst component and catalyst system having a high polymerization activity for preparing polymers KAMINSKY WALTER (DE) 2002-10-03 US disclosed
US-6303718-B1 PARTICULARLY A CATALYST SYSTEM CONSISTING OF METALLOCENE FLUORIDES AND ALUMINUM ALKYLS BAYER AKTIENGESELLSCHAFT (DE) 2001-10-16 US disclosed