SCHEMBL7602852

SCHEMBL7602852

O=C(NC(=O)c1c(Cl)cccc1Cl)Nc1ccc(F)cc1F

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.60
KMT2A Q03164 2/20 0.60
PKM P14618 2/20 0.60
LMNA P02545 1/20 0.60
MEN1 O00255 1/20 0.55
RAB9A P51151 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
NPC1 O15118 2/20 0.54
HTT P42858 2/20 0.54
PYGL P06737 1/20 0.49
TP53 P04637 2/20 0.49
ALDH1A1 P00352 1/20 0.48
POLB P06746 1/20 0.48
TAS1R3 Q7RTX0 1/20 0.48
TAS1R1 Q7RTX1 1/20 0.48
TAS1R2 Q8TE23 1/20 0.48
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30499671 1.00 GAA (0.60) GAAKMT2APKMLMNAMEN1
SCHEMBL9352497 0.89 KMT2A (0.55) GAAKMT2APKMLMNAMEN1
SCHEMBL8657856 0.87 KMT2A (0.59) GAAKMT2APKMLMNAMEN1
SCHEMBL30499690 0.86 KMT2A (0.53) GAAKMT2APKMLMNAMEN1
SCHEMBL7603582 0.86 KMT2A (0.53) GAAKMT2APKMLMNAMEN1
SCHEMBL9348863 0.84 KMT2A (0.59) KMT2ALMNAMEN1RAB9ASMN1; SMN2
SCHEMBL30499681 0.84 NPC1 (0.54) GAAKMT2APKMLMNAMEN1
SCHEMBL7600018 0.84 NPC1 (0.54) GAAKMT2APKMLMNAMEN1
SCHEMBL13235108 0.83 KMT2A (0.50) GAAKMT2APKMLMNAMEN1
SCHEMBL9352535 0.80 RAB9A (0.61) KMT2APKMLMNAMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US claimed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
WO-1997045017-A1 BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-12-04 WO claimed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed
US-6057370-A APPLYING TO THE FOLIAGE OF SAID GENETICALLY ALTERED COTTON PLANT AN ENHANCED PESTICIDALLY ACTIVE AMOUNT OF A SUBSTITUTED BENZOYL UREA MACDERMID AGRICULTURAL SOLUTIONS, INC. 2000-05-02 US disclosed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO disclosed
US-4564639-A INSECTICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-01-14 US disclosed
EP-0088343-B1 UREA DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1985-07-03 EP disclosed
EP-0088343-A2 Urea derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1983-09-14 EP disclosed
US-4166124-A IMIDAZOLE OR PYRIMIDINE RINGS U.S. PHILIPS CORPORATION (US) 1979-08-28 US disclosed
US-4110469-A Insecticidal N-(2,6-dichlorobenzoyl)-N'-(4-cyanophenyl) urea U.S. PHILIPS CORPORATION (US) 1978-08-29 US disclosed
US-4013717-A BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES U.S. PHILIPS CORPORATION (US) 1977-03-22 US disclosed
US-3989842-A Certain substituted benzoyl urea insecticides U.S. PHILIPS CORPORATION (US) 1976-11-02 US disclosed
US-3933908-A INSECTICIDE U.S. PHILIPS CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 GAA 1890/4885KMT2A 2393/4885PKM 4573/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 GAA 1890/4885KMT2A 2393/4885PKM 4573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.