SCHEMBL7603582

SCHEMBL7603582

O=C(NC(=O)c1c(Cl)cccc1Cl)Nc1ccc(I)cc1F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.53
MEN1 O00255 4/20 0.53
LMNA P02545 2/20 0.45
GAA P10253 1/20 0.45
PKM P14618 1/20 0.45
MAPT P10636 2/20 0.43
USP2 O75604 1/20 0.43
ALOX15 P16050 1/20 0.43
PPIA P62937 2/20 0.43
JAK2 O60674 2/20 0.42
JAK1 P23458 2/20 0.42
TYK2 P29597 2/20 0.42
RAB9A P51151 2/20 0.41
PYGL P06737 1/20 0.41
HTT P42858 1/20 0.41
PTGFR P43088 1/20 0.41
ATM Q13315 1/20 0.41
CYP3A4 P08684 1/20 0.40
NPC1 O15118 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30499690 1.00 KMT2A (0.53) KMT2AMEN1LMNAGAAPKM
SCHEMBL8658188 0.88 MEN1 (0.56) KMT2AMEN1LMNAGAAPKM
SCHEMBL30499671 0.86 GAA (0.60) KMT2AMEN1LMNAGAAPKM
SCHEMBL7602852 0.86 GAA (0.60) KMT2AMEN1LMNAGAAPKM
SCHEMBL9348863 0.82 KMT2A (0.59) KMT2AMEN1LMNAMAPTPPIA
SCHEMBL13235108 0.81 KMT2A (0.50) KMT2AMEN1LMNAGAAPKM
SCHEMBL7600018 0.79 NPC1 (0.54) KMT2AMEN1LMNAGAAPKM
SCHEMBL30499681 0.79 NPC1 (0.54) KMT2AMEN1LMNAGAAPKM
SCHEMBL9352497 0.78 KMT2A (0.55) KMT2AMEN1LMNAGAAPKM
SCHEMBL5316465 0.78 KMT2A (0.55) KMT2AMEN1LMNAGAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US claimed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
WO-1997045017-A1 BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-12-04 WO claimed
US-4243680-A N-(2,6-DIHALOBENZOYL)-N'-(HALOGENATED PHENYL) UREA; LARVICIDES THOMPSON-HAYWARD CHEMICAL COMPANY (US) 1981-01-06 US claimed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed
US-6057370-A APPLYING TO THE FOLIAGE OF SAID GENETICALLY ALTERED COTTON PLANT AN ENHANCED PESTICIDALLY ACTIVE AMOUNT OF A SUBSTITUTED BENZOYL UREA MACDERMID AGRICULTURAL SOLUTIONS, INC. 2000-05-02 US disclosed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO disclosed
US-4607044-A Insecticidal use of ureas and thioureas DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1986-08-19 US disclosed
US-4243680-A N-(2,6-DIHALOBENZOYL)-N'-(HALOGENATED PHENYL) UREA; LARVICIDES THOMPSON-HAYWARD CHEMICAL COMPANY (US) 1981-01-06 US disclosed
US-4166124-A IMIDAZOLE OR PYRIMIDINE RINGS U.S. PHILIPS CORPORATION (US) 1979-08-28 US disclosed
US-4110469-A Insecticidal N-(2,6-dichlorobenzoyl)-N'-(4-cyanophenyl) urea U.S. PHILIPS CORPORATION (US) 1978-08-29 US disclosed
US-4013717-A BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES U.S. PHILIPS CORPORATION (US) 1977-03-22 US disclosed
US-3989842-A Certain substituted benzoyl urea insecticides U.S. PHILIPS CORPORATION (US) 1976-11-02 US disclosed
US-3933908-A INSECTICIDE U.S. PHILIPS CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 KMT2A 2393/4885MEN1 980/4885LMNA 3523/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 KMT2A 2393/4885MEN1 980/4885LMNA 3523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.