SCHEMBL300285

SCHEMBL300285

CC(=O)CC(=O)Nc1ccccc1Cl

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.66
MEN1 O00255 3/20 0.66
HTT P42858 1/20 0.59
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
HPGD P15428 3/20 0.55
POLB P06746 1/20 0.55
ALDH1A1 P00352 2/20 0.53
MAPT P10636 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C19 P33261 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29554472 1.00 KMT2A (0.66) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL9311985 0.88 KMT2A (0.75) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL2912340 0.86 MAPT (0.58) KMT2AMEN1HTTRAB9AHPGD
SCHEMBL12720508 0.86 MEN1 (0.80) KMT2AMEN1POLBALDH1A1MAPT
SCHEMBL11577296 0.84 LMNA (0.64) KMT2AMEN1HPGDPOLBALDH1A1
SCHEMBL11441867 0.83 ALDH1A1 (0.52) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL17434797 0.83 KMT2A (0.68) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL2169180 0.83 MEN1 (0.68) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL29389982 0.83 KMT2A (0.68) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL5186995 0.83 MEN1 (0.68) KMT2AMEN1HTTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115746579-A Preparation method of high level-dyeing-property-based dye product 宁夏保隆科技有限公司 2023-03-07 CN claimed
WO-2022228846-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-11-03 WO claimed
WO-2022117389-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-06-09 WO claimed
CN-108997774-B Method for producing organic cobalt complex 金华双宏化工有限公司 2020-06-26 CN claimed
CN-109971201-A A kind of preparation method of everbright fast yellow organic pigment 龙口祥耀化学科技有限公司 2019-07-05 CN claimed
CN-108997774-A The manufacturing method of organic cobalt complex 金华双宏化工有限公司 2018-12-14 CN claimed
EP-2280932-B1 Process for preparing substituted biphenylanilides BAYER IP GMBH (DE) 2017-10-18 EP claimed
US-9575038-B2 Universal detector calibrant THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2017-02-21 US claimed
US-9250222-B2 Universal detector calibrant THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2016-02-02 US claimed
CN-102482195-B Tetraarylborate process for producing substituted biphenyls BAYER CROPSCIENCE AG 2015-04-01 CN claimed
EP-0451094-B1 Process for the production of pigments CIBA GEIGY AG (CH) 1995-02-01 EP claimed
US-5352281-A Containing nonionic surfactant with specified cloud point HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-04 US claimed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP claimed
EP-0587021-A1 Use of preparations of azo-pigments containing solvents for intaglio printing and flexographic printing on packaging HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-16 EP claimed
EP-0529849-A1 Coupling process CIBA-GEIGY AG (CH) 1993-03-03 EP claimed
US-5151129-A Precipitation of pigments and coupling CIBA-GEIGY CORPORATION (US) 1992-09-29 US claimed
EP-0451094-A1 Process for the production of pigments CIBA-GEIGY AG (CH) 1991-10-09 EP claimed
US-4780533-A REACTION PRODUCT OF TETRAZO COMPOUND OF 3,3'-DICHLOROBENZIDINE AND ACETOANILIDE DERIVATIVE DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1988-10-25 US claimed
US-4648907-A 3,3*-DICHLOROBENZIDINE, DIAZOTIZATION, COUPLING, ACETOACETARYLIDES, MULTISTAGE, INKS BASF CORPORATION (US) 1987-03-10 US claimed
US-4304711-A PLASTIC MASS AND MONOAZO DYE CIBA-GEIGY CORPORATION (US) 1981-12-08 US claimed