Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598993 | 0.87 | MAPT (0.39) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL7597575 | 0.86 | MAPT (0.39) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7603824 | 0.85 | LMNA (0.38) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL7600294 | 0.84 | LMNA (0.38) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7066492 | 0.83 | MAPT (0.38) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7065983 | 0.82 | MAPT (0.37) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7069540 | 0.82 | MAPT (0.39) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7066027 | 0.81 | MAPT (0.41) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7070221 | 0.81 | MAPT (0.38) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7066511 | 0.81 | PPARA (0.44) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266888-A1 | QUINOLINE DERIVATIVES AND MEDICINAL USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2002-12-18 | — | — | EP | disclosed |