SCHEMBL7603499

SCHEMBL7603499

CCCCCCCC(CCCCO)C(C)(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 1/20 0.41
CSNK1E P49674 1/20 0.40
PRSS1 P07477 2/20 0.39
CTSG P08311 2/20 0.39
CTRB1 P17538 2/20 0.39
CMA1 P23946 2/20 0.39
SPHK1 Q9NYA1 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
MAPK1 P28482 1/20 0.37
HDAC8 Q9BY41 4/20 0.36
HDAC3 O15379 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
MMP12 P39900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7605249 1.00 LMNA (0.41) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL7608542 0.92 MEN1 (0.35) LMNAALDH1A1MEN1KMT2ACSNK1E
SCHEMBL11177019 0.92 CSNK1E (0.41) ALDH1A1MEN1KMT2ACSNK1EPRSS1
Hydrogen Peroxide SCHEMBL9456660 0.79 ALDH1A1 (0.46) ALDH1A1HSD17B10MEN1KMT2ACSNK1E
SCHEMBL7616178 0.77 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ACSNK1EPRSS1
SCHEMBL29160983 0.77 CSNK1E (0.44) ALDH1A1MEN1KMT2ACSNK1EPRSS1
SCHEMBL29780652 0.77 CSNK1E (0.44) ALDH1A1MEN1KMT2ACSNK1EPRSS1
SCHEMBL18660141 0.77 CSNK1E (0.44) ALDH1A1CSNK1EPRSS1CTSGCTRB1
SCHEMBL7005026 0.76 BID (0.42) HSD17B10MMP2
SCHEMBL7005030 0.76 ESR1 (0.51) LMNAALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704437-B1 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA SC HOLDING AG (CH) 2002-09-25 EP disclosed
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP disclosed