Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505144 | 0.85 | PTGER4 (0.49) | RAB9AMEN1KMT2ANPC1NPSR1 | |
| SCHEMBL29878719 | 0.85 | PTGER4 (0.49) | RAB9AMEN1KMT2ANPC1NPSR1 | |
| SCHEMBL7598707 | 0.83 | POLB (0.55) | RAB9AMEN1KMT2ANPC1NPSR1 | |
| SCHEMBL26631782 | 0.82 | NPSR1 (0.46) | RAB9AMEN1KMT2ANPC1NPSR1 | |
| SCHEMBL29989408 | 0.80 | MEN1 (0.52) | RAB9AMEN1KMT2ANPC1NPSR1 | |
| SCHEMBL7796764 | 0.80 | ALDH1A1 (0.55) | NPSR1PTGER4MAPTNOD2HTT | |
| SCHEMBL7607379 | 0.79 | MEN1 (0.45) | RAB9AMEN1KMT2ANPC1NPSR1 | |
| SCHEMBL5066621 | 0.78 | POLB (0.44) | RAB9AMEN1KMT2ANPC1NPSR1 | |
| SCHEMBL7601817 | 0.78 | MEN1 (0.64) | RAB9AMEN1KMT2ANPC1NPSR1 | |
| SCHEMBL13537327 | 0.78 | MEN1 (0.50) | RAB9AMEN1KMT2ANPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264825-A1 | Beta-Hydroxyalkylpicoliniumsalts | Bayer Aktiengesellschaft (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-5840902-A | REACTING PICOLINE WITH ALKYLENE OXIDE IN PRESENCE OF ACID IN WATER OR MIXTURE OF WATER AND POLAR SOLVENT | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0776888-A2 | Process for the preparation of beta-Hydrosyalkylpicolinium salts and picolinium salts as intermediates for the prepation of cationic dyes | BAYER AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-4513142-A | Preparation of cationic methine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-04-23 | — | — | US | disclosed |
| EP-0074569-A2 | Cationic methine dyes, process for their preparation and their use, in dyeing textile materials and other substrates | BAYER AG (DE) | 1983-03-23 | — | — | EP | disclosed |