Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 12/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601837 | 0.91 | ALDH1A1 (0.68) | ALDH1A1LMNANPSR1MAPTHTT | |
| SCHEMBL10821003 | 0.85 | ALDH1A1 (0.77) | ALDH1A1LMNANPSR1MAPTHTT | |
| SCHEMBL7796917 | 0.81 | TACR1 (0.41) | MAPTTACR1KDM4EHCRTR1CASP1 | |
| SCHEMBL7798970 | 0.81 | TACR1 (0.44) | TACR1 | |
| SCHEMBL8505144 | 0.81 | PTGER4 (0.49) | ALDH1A1LMNANPSR1MAPTHTT | |
| SCHEMBL29878719 | 0.81 | PTGER4 (0.49) | ALDH1A1LMNANPSR1MAPTHTT | |
| SCHEMBL7603554 | 0.80 | RAB9A (0.52) | ALDH1A1LMNANPSR1MAPTHTT | |
| SCHEMBL26631782 | 0.78 | NPSR1 (0.46) | ALDH1A1LMNANPSR1MAPTHTT | |
| SCHEMBL7790320 | 0.76 | TACR1 (0.54) | TACR1 | |
| SCHEMBL7603632 | 0.75 | LMNA (0.70) | ALDH1A1LMNANPSR1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010039286-A1 | 2-aryl indole derivatives and their use as therapeutic agents | DINNELL KEVIN (GB) | 2001-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039286-A1 | 2-aryl indole derivatives and their use as therapeutic agents | IDO1, IDO2, CNR2 | ALDH1A1 410/4885LMNA 2005/4885NPSR1 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.