Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311223 | 0.91 | ATM (0.56) | KMT2AMEN1PKMUSP2MAPT | |
| SCHEMBL5316460 | 0.83 | ATM (0.57) | KMT2AMEN1GAALMNAPKM | |
| SCHEMBL10762060 | 0.81 | KMT2A (0.61) | KMT2AMEN1GAALMNAPKM | |
| SCHEMBL30499671 | 0.80 | GAA (0.60) | KMT2AMEN1GAALMNAPKM | |
| SCHEMBL7602852 | 0.80 | GAA (0.60) | KMT2AMEN1GAALMNAPKM | |
| SCHEMBL14546321 | 0.79 | KMT2A (0.49) | KMT2AMEN1GAALMNAPKM | |
| SCHEMBL10507936 | 0.79 | KMT2A (0.48) | KMT2AMEN1GAALMNAPKM | |
| SCHEMBL8660904 | 0.78 | KMT2A (0.64) | KMT2AMEN1GAALMNAPKM | |
| SCHEMBL6511477 | 0.78 | KMT2A (0.52) | KMT2AMEN1GAALMNAPKM | |
| SCHEMBL9348863 | 0.78 | KMT2A (0.59) | KMT2AMEN1LMNAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |