Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603620 | 1.00 | CASP3 (0.69) | CASP3SENP7SMN1; SMN2SENP6KDM4E | |
| SCHEMBL7603736 | 0.93 | SMN1; SMN2 (0.76) | CASP3SENP7SMN1; SMN2SENP6KDM4E | |
| SCHEMBL7885065 | 0.93 | KDM4E (0.70) | CASP3SENP7SMN1; SMN2SENP6KDM4E | |
| SCHEMBL7885069 | 0.93 | KDM4E (0.70) | CASP3SENP7SMN1; SMN2SENP6KDM4E | |
| SCHEMBL11563569 | 0.90 | CASP3 (0.71) | CASP3SENP7SMN1; SMN2SENP6KDM4E | |
| SCHEMBL231011 | 0.87 | NPC1 (0.67) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL19690361 | 0.87 | NPC1 (0.67) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL29924255 | 0.87 | NPC1 (0.67) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL29924607 | 0.87 | NPC1 (0.67) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL29405696 | 0.87 | NPC1 (0.67) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265876-A1 | PREPARATION OF MIXTURES OF BENZOXAZOLYL-STILBENE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001064658-A1 | PREPARATION OF MIXTURES OF BENZOXAZOLYL-STILBENE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2001-09-07 | — | — | WO | disclosed |
| US-6177574-B1 | REACTING 4,4'-BIS(BENZOXAZOL-2-YL)STILBENE WITH AN AMINOPHENOL AT A TEMPERATURE OF AT LEAST 200 DEGREES C IN THE PRESENCE OF AN INERT ORGANIC SOLVENT | EASTMAN CHEMICAL COMPANY | 2001-01-23 | — | — | US | disclosed |