Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.76 |
| ▸ | CASP3 | P42574 | 5/20 | 0.76 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.76 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CETP | P11597 | 4/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885069 | 0.94 | KDM4E (0.70) | SMN1; SMN2CASP3SENP7SENP6KDM4E | |
| SCHEMBL7885065 | 0.94 | KDM4E (0.70) | SMN1; SMN2CASP3SENP7SENP6KDM4E | |
| SCHEMBL7603618 | 0.93 | CASP3 (0.69) | SMN1; SMN2CASP3SENP7SENP6KDM4E | |
| SCHEMBL7603620 | 0.93 | CASP3 (0.69) | SMN1; SMN2CASP3SENP7SENP6KDM4E | |
| SCHEMBL11563569 | 0.91 | CASP3 (0.71) | SMN1; SMN2CASP3SENP7SENP6KDM4E | |
| SCHEMBL24881857 | 0.87 | SMN1; SMN2 (0.94) | SMN1; SMN2CASP3SENP7SENP6KDM4E | |
| SCHEMBL2141073 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2CASP3SENP7SENP6KDM4E | |
| SCHEMBL30729297 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2CASP3SENP7SENP6KDM4E | |
| SCHEMBL9858039 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2CASP3SENP7SENP6KDM4E | |
| SCHEMBL7609308 | 0.83 | SMN1; SMN2 (0.76) | SMN1; SMN2CASP3SENP7SENP6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265876-A1 | PREPARATION OF MIXTURES OF BENZOXAZOLYL-STILBENE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001064658-A1 | PREPARATION OF MIXTURES OF BENZOXAZOLYL-STILBENE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2001-09-07 | — | — | WO | disclosed |