Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 16/20 | 0.62 |
| ▸ | ADRA1B | P35368 | 12/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 11/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7632730 | 0.80 | ADRA1A (0.45) | ADRA1AADRA1BADRA1D | |
| SCHEMBL7639413 | 0.80 | ADRA1A (0.46) | ADRA1AADRA1BADRA1D | |
| SCHEMBL7584002 | 0.79 | ADRA1A (0.45) | ADRA1AADRA1BADRA1D | |
| SCHEMBL6366182 | 0.77 | ADRA1A (1.00) | ADRA1AADRA1BADRA1D | |
| Hydrochloric Acid SCHEMBL7630026 | 0.76 | ADRA1A (0.46) | ADRA1AADRA1BADRA1D | |
| SCHEMBL6425373 | 0.69 | ADRA1A (1.00) | ADRA1AADRA1BADRA1D | |
| SCHEMBL7633527 | 0.69 | TAAR1 (0.45) | ADRA1AADRA1BADRA1D | |
| SCHEMBL6367034 | 0.67 | ADRA1A (0.81) | ADRA1AADRA1BADRA1D | |
| Hydrochloric Acid SCHEMBL7632791 | 0.66 | ADRA1A (0.53) | ADRA1AADRA1BADRA1DTP53 | |
| Fumaric Acid SCHEMBL7640065 | 0.65 | ADRA1A (0.41) | ADRA1AADRA1BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175406-A1 | IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066563-A1 | IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2000-11-09 | — | — | WO | disclosed |