Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969842 | 0.81 | NPC1 (0.30) | RAB9AMAPTNPC1SMN1; SMN2TP53 | |
| SCHEMBL9522187 | 0.79 | KDM4E (0.44) | ALDH1A1KDM4EHPGDRAB9AMAPT | |
| SCHEMBL7919531 | 0.77 | MAPT (0.33) | RAB9AMAPTNPC1SMN1; SMN2TP53 | |
| SCHEMBL7603698 | 0.75 | MAPT (0.39) | ALDH1A1KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL8051713 | 0.74 | MAOB (0.40) | RAB9AMAPTNPC1SMN1; SMN2THRB | |
| SCHEMBL9363731 | 0.74 | MAPT (0.32) | MAPT | |
| SCHEMBL7059454 | 0.74 | MEN1 (0.38) | ALDH1A1KDM4EHPGDRAB9AMAPT | |
| SCHEMBL8057087 | 0.74 | MAPT (0.38) | ALDH1A1KDM4EHPGDRAB9AMAPT | |
| SCHEMBL8049797 | 0.73 | HTT (0.35) | ALDH1A1KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL8050773 | 0.73 | MAPT (0.33) | RAB9AMAPTNPC1SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |