SCHEMBL760372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11577531	0.79	NOS1 (0.53)	NOS1MAPTKDM4EMEN1KMT2A
	SCHEMBL2425031	0.78	NOS1 (0.52)	NOS1MAPTCHEK1METAP2DYRK1A
	SCHEMBL1286200	0.76	MAPT (0.52)	NOS1MAPTROCK1KDM4EMEN1
	SCHEMBL759126	0.76	NOS1 (0.50)	NOS1MAPTROCK1KDM4EMEN1
	SCHEMBL3515094	0.76	MAPT (0.46)	NOS1MAPTROCK1KDM4EMEN1
	SCHEMBL30099420	0.76	NOS1 (0.50)	NOS1MAPTCHEK1METAP2DYRK1A
	SCHEMBL2430496	0.76	NOS1 (0.50)	NOS1MAPTMEN1KMT2ACHEK1
	SCHEMBL14500106	0.76	NOS1 (0.50)	NOS1MAPTKDM4EALDH1A1HTT
	Hydrochloric Acid SCHEMBL15517276	0.74	MAPT (0.50)	MAPTROCK1KDM4EMEN1KMT2A
	SCHEMBL25475118	0.73	KDM4E (0.43)	MAPTROCK1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.