Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 3/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094429 | 0.84 | P2RY6 (0.66) | P2RY6HSD17B10CA1CA2MIF | |
| SCHEMBL7686608 | 0.83 | P2RY6 (0.63) | P2RY6HSD17B10CHRM1GRIN1GRIN2A | |
| SCHEMBL9547715 | 0.79 | P2RY6 (1.00) | P2RY6HSD17B10CHRM1CA1CA2 | |
| SCHEMBL1853024 | 0.79 | P2RY6 (1.00) | P2RY6HSD17B10CHRM1CA1CA2 | |
| SCHEMBL9135914 | 0.79 | FFAR1 (0.50) | HSD17B10CA1CA2CYP3A4TP53 | |
| SCHEMBL3763772 | 0.79 | P2RY6 (0.58) | P2RY6HSD17B10NAAA | |
| SCHEMBL3397221 | 0.78 | P2RY6 (0.61) | P2RY6HSD17B10MIFNAAACYP1A2 | |
| SCHEMBL8503279 | 0.76 | P2RY6 (0.76) | P2RY6HSD17B10CHRM1GRIN1GRIN2A | |
| SCHEMBL347652 | 0.74 | P2RY6 (0.79) | P2RY6HSD17B10CHRM1GRIN1GRIN2A | |
| SCHEMBL9785601 | 0.73 | P2RY6 (0.70) | P2RY6HSD17B10CHRM1GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624377-B1 | Lysosomal enzyme-cleavable antitumor drug conjugates | BRISTOL MYERS SQUIBB CO (US) | 2002-01-23 | — | — | EP | disclosed |
| US-6132697-A | RADIOACTIVE MATERIAL DRUGS | G. D. SEARLE & CO. (US) | 2000-10-17 | — | — | US | disclosed |