SCHEMBL3397221

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1094429	0.90	P2RY6 (0.66)	P2RY6FFAR1HSD17B10LMNAMIF
	SCHEMBL6208836	0.80	SMN1; SMN2 (0.82)	SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4
	SCHEMBL1457228	0.79	P2RY6 (0.59)	P2RY6FFAR1HSD17B10MAPTALDH1A1
	Tromethamine SCHEMBL8642774	0.78	P2RY6 (0.50)	P2RY6MAPK1HSD17B10NAAA
	SCHEMBL7603799	0.78	P2RY6 (0.63)	P2RY6FFAR1HSD17B10CYP2D6TSHR
	SCHEMBL7686608	0.78	P2RY6 (0.63)	P2RY6HSD17B10CYP2D6ALDH1A1LMNA
	SCHEMBL1853024	0.78	P2RY6 (1.00)	P2RY6HSD17B10CYP2D6TSHRHIF1A
	SCHEMBL9547715	0.78	P2RY6 (1.00)	P2RY6HSD17B10CYP2D6TSHRHIF1A
	SCHEMBL69789	0.78	SMN1; SMN2 (0.78)	SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4
	SCHEMBL13468985	0.77	SMN1; SMN2 (0.60)	SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.