Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12077937 | 0.89 | NPSR1 (0.60) | SLC6A2SLC6A4NPSR1KDM4EMEN1 | |
| SCHEMBL3553137 | 0.85 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2NPSR1 | |
| SCHEMBL3561029 | 0.85 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2NPSR1 | |
| SCHEMBL14628370 | 0.84 | NPSR1 (0.72) | NPSR1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL3557754 | 0.83 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNH2NPSR1 | |
| Hydrochloric Acid SCHEMBL4777138 | 0.82 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3KCNH2NPSR1 | |
| SCHEMBL4693454 | 0.81 | ESR2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2ESR2 | |
| SCHEMBL3485687 | 0.80 | ALDH1A1 (0.71) | SLC6A2SLC6A4KDM4EMEN1ALDH1A1 | |
| SCHEMBL7608221 | 0.79 | USP2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2KMT2A | |
| Hydrochloric Acid SCHEMBL27714396 | 0.78 | ALDH1A1 (0.69) | SLC6A2SLC6A4KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020094989-A1 | Pyrrolidine modulators of CCR5 chemokine receptor activity | HALE JEFFREY J (US) | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094989-A1 | Pyrrolidine modulators of CCR5 chemokine receptor activity | CCR5, CCR1, CXCR1 | SLC6A2 4324/4885SLC6A4 3680/4885SLC6A3 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.