Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12999035 | 0.84 | ADRB1 (0.47) | ADRB1AKR1C3MAPTLMNAGAA | |
| SCHEMBL737608 | 0.82 | HSD17B10 (0.52) | SLC6A2SLC6A4SLC6A3ADRB1AKR1C3 | |
| SCHEMBL6078859 | 0.79 | CYP2C9 (0.53) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17665167 | 0.78 | ADRB1 (0.52) | ADRB1AKR1C3MAPTLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL6078571 | 0.78 | CYP2C9 (0.51) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10643802 | 0.77 | ALDH1A1 (0.53) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL26406889 | 0.74 | ADRB1 (0.52) | ADRB1PTPN11AKR1C3MAPTSMN1; SMN2 | |
| SCHEMBL760255 | 0.73 | ADRB1 (0.40) | ADRB1AKR1C3MAPTGAASMN1; SMN2 | |
| SCHEMBL17543949 | 0.73 | ADRB1 (0.50) | ADRB1AKR1C3MAPTGAAKDM4E | |
| SCHEMBL20694433 | 0.72 | ADRB1 (0.46) | ADRB1AKR1C3MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138206-B2 | Piperidine derivative | MSD. K.K. (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20090137576-A1 | Novel Piperidine Derivative | MSD K.K. (JP) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137576-A1 | Novel Piperidine Derivative | HRH4, HRH3, HRH1 | SLC6A2 971/4885SLC6A4 522/4885SLC6A3 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.