SCHEMBL7604286

SCHEMBL7604286

Cc1ccc2cc(-c3noc(C)n3)ccc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.62
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
PLK1 P53350 1/20 0.47
RAB9A P51151 7/20 0.47
NFKB1 P19838 2/20 0.47
NFKB2 Q00653 2/20 0.47
RELA Q04206 2/20 0.47
LMNA P02545 2/20 0.47
TSHR P16473 2/20 0.47
CYP1A2 P05177 2/20 0.46
CYP2A6 P11509 1/20 0.46
POLB P06746 1/20 0.46
NPC1 O15118 6/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
TP53 P04637 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7996145 0.95 L3MBTL1 (0.61) L3MBTL1CA12CA1CA2CA9
SCHEMBL2055354 0.83 L3MBTL1 (0.59) L3MBTL1CA12CA1CA2CA9
SCHEMBL2967349 0.83 L3MBTL1 (0.62) L3MBTL1CA12CA1CA2CA9
SCHEMBL13415301 0.80 L3MBTL1 (0.69) L3MBTL1CA12CA1CA2CA9
SCHEMBL2090313 0.80 L3MBTL1 (0.82) L3MBTL1RAB9ANFKB1NFKB2RELA
SCHEMBL2055350 0.79 L3MBTL1 (0.54) L3MBTL1CA12CA1CA2CA9
SCHEMBL12267104 0.78 L3MBTL1 (0.67) L3MBTL1CA12CA1CA2CA9
SCHEMBL13130238 0.77 L3MBTL1 (1.00) L3MBTL1CA12CA1CA2CA9
SCHEMBL25259119 0.77 L3MBTL1 (0.56) L3MBTL1CA12CA1CA2CA9
SCHEMBL12601899 0.76 NPC1 (0.54) L3MBTL1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304554-B2 Compound, composition and thin film FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-20120229734-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-8184247-B2 TN-mode liquid crystal display device, optical compensatory film for use therein and method for producing optical compensatory film, and polarizing plate FUJIFILM CORPORATION (JP) 2012-05-22 US disclosed
US-8164722-B2 Liquid-crystal display device with at least three optically-anisotropic layers having formulated in-plane retardations FUJIFILM CORPORATION (JP) 2012-04-24 US disclosed
US-20110311738-A1 Process of producing cellulose acylate film, cellulose acylate film, polarizing plate liquid crystal display device and optical compensation film FUJIFILM CORPORATION (JP) 2011-12-22 US disclosed
US-8053040-B2 Liquid crystal composition, retardation plate, liquid crystal display device, and process for producing retardation plate FUJIFILM CORPORATION (JP) 2011-11-08 US disclosed
US-8025933-B2 Optical anisotropic layer FUJIFILM CORPORATION (JP) 2011-09-27 US disclosed
US-8025936-B2 Optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-09-27 US disclosed
US-7998542-B2 Composition, retardation plate, liquid-crystal display device, and method for producing retardation plate FUJIFILM CORPORATION (JP) 2011-08-16 US disclosed
US-7989037-B2 A layer of discotic liquid-crystal and an anisotropic fluoropolymer of acrylic esters, e.g., 4-((4-nitrilophenoxy)butyl acrylate /2-(perfluorhexyl)ethyl acrylate copolymer; providing stability/optical compensation; no defects from optical fluctuation or alignment failure; controlling the tilt angle FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
WO-2008153201-A1 LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2008-12-18 WO disclosed
US-20080291369-A1 Optical Film, Optical Compensation Film, Polarizing Plate, and Liquid-Crystal Display Device FUJIFILM CORPORATION (JP) 2008-11-27 US disclosed
US-7431971-B2 Retardation plate FUJIFILM CORPORATION (JP) 2008-10-07 US disclosed
WO-2008111685-A1 LIQUID CRYSTAL COMPOSITION, RETARDATION PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND PROCESS FOR PRODUCING RETARDATION PLATE FUJIFILM CORPORATION (JP) 2008-09-18 WO disclosed
US-20080193679-A1 Optical anisotropic layer FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080113112-A1 Optical Compensation Film, Method of Producing the Same, and Polarizing Plate and Liquid Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-05-15 US disclosed
US-20080090027-A1 Composition, retardation plate, and liquid-crystal display device FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed
US-20080075892-A1 Optically-Anisotropic Film and Liquid-Crystal Display Device FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080064879-A1 Compound ,Composition And Thin Film FUJIFILM CORPORATION (JP) 2008-03-13 US disclosed
WO-2007064039-A1 OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-06-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080193679-A1 Optical anisotropic layer YBX1, YBX3, H1-2 L3MBTL1 156/4885CA12 964/4885CA1 2815/4885
US-20080075892-A1 Optically-Anisotropic Film and Liquid-Crystal Display Device L1CAM, CRY1, TLN1 L3MBTL1 119/4885CA12 3178/4885CA1 1471/4885
US-20080064879-A1 Compound ,Composition And Thin Film YBX1, H1-2, YBX3 L3MBTL1 724/4885CA12 256/4885CA1 1556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.