Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 5/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610423 | 0.91 | ACP3 (0.38) | ACP3HPGDFOLH1CYP2D6CYP1A2 | |
| SCHEMBL7610582 | 0.88 | GABBR2 (0.43) | ACP3FOLH1CYP2D6CYP1A2PKM | |
| SCHEMBL7608351 | 0.87 | ALDH1A1 (0.39) | ACP3FOLH1CYP2D6CYP1A2PKM | |
| SCHEMBL7608422 | 0.84 | ACP3 (0.40) | ACP3FOLH1CYP2D6SMN1; SMN2 | |
| SCHEMBL7606733 | 0.83 | ANPEP (0.40) | ACP3FOLH1 | |
| SCHEMBL28574296 | 0.83 | ACP3 (0.56) | ACP3FOLH1 | |
| SCHEMBL3380506 | 0.77 | ANPEP (0.40) | FOLH1PKM | |
| SCHEMBL8734087 | 0.75 | HDAC3 (0.47) | HPGDFOLH1SMN1; SMN2NPSR1 | |
| SCHEMBL8154438 | 0.72 | TSHR (0.49) | SMN1; SMN2 | |
| SCHEMBL8457131 | 0.72 | TSHR (0.49) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002515040-A | — | — | 2002-05-21 | — | — | JP | claimed |
| EP-0954295-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-10 | — | — | EP | claimed |
| WO-1997048409-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1997-12-24 | — | — | WO | claimed |