SCHEMBL76048

SCHEMBL76048

C=CC(=O)Oc1ccc(-c2ncc(CCCCCC)cn2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 8/20 0.67
▸ RARB P10826 4/20 0.63
▸ SMN1; SMN2 Q16637 4/20 0.51
▸ MAPT P10636 3/20 0.51
▸ RAB9A P51151 5/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ HSD17B10 Q99714 2/20 0.50
▸ USP2 O75604 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ GAA P10253 1/20 0.50
▸ HPGD P15428 1/20 0.50
▸ THRA P10827 6/20 0.49
▸ NPC1 O15118 3/20 0.45
▸ NFKB1 P19838 1/20 0.45
▸ NFKB2 Q00653 1/20 0.45
▸ RELA Q04206 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ CASP3 P42574 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13446673 1.00 THRB (0.67) THRBRARBSMN1; SMN2MAPTRAB9A
SCHEMBL75102 1.00 THRB (0.67) THRBRARBSMN1; SMN2MAPTRAB9A
SCHEMBL815928 0.99 THRB (0.69) THRBRARBSMN1; SMN2MAPTRAB9A
SCHEMBL14571749 0.86 THRB (0.54) THRBRARBSMN1; SMN2MAPTRAB9A
SCHEMBL16425791 0.86 MAPT (0.53) THRBRARBSMN1; SMN2MAPTMEN1
SCHEMBL9817695 0.85 RARB (0.70) THRBRARBSMN1; SMN2MAPTRAB9A
SCHEMBL9817321 0.85 RARB (0.70) THRBRARBSMN1; SMN2MAPTRAB9A
SCHEMBL9817470 0.85 RARB (0.70) THRBRARBSMN1; SMN2MAPTRAB9A
SCHEMBL9817442 0.85 RARB (0.70) THRBRARBSMN1; SMN2MAPTRAB9A
SCHEMBL9817342 0.85 RARB (0.70) THRBRARBSMN1; SMN2MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8139189-B2 Liquid crystal display having particular oblique vapor deposition-alignment layer with ferroelectric liquid crystal DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-20 — — US disclosed
US-8130358-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-06 — — US disclosed
US-8009266-B2 Process for producing liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2011-08-30 — — US disclosed
US-7892449-B2 Liquid crystal display and manufacturing method of same DAI NIPPON PRINTING CO., LTD. (JP) 2011-02-22 — — US disclosed
US-7871540-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2011-01-18 — — US disclosed
US-7777847-B2 Liquid crystal display and manufacturing method of the same DAI NIPPON PRINTING CO., LTD. (JP) 2010-08-17 — — US disclosed
US-20100060844-A1 PROCESS FOR PRODUCING LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-03-11 — — US disclosed
US-20100053525-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-03-04 — — US disclosed
US-20100007832-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-01-14 — — US disclosed
US-7570331-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-04 — — US disclosed
US-7499135-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-03-03 — — US disclosed
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2009-02-26 — — US disclosed
US-20070026165-A1 Liquid crystal display and manufacturing method of same DAI NIPPON PRINTING CO., LTD. (JP) 2007-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION H1-0, H1-4, H1-10 THRB 3657/4885RARB 3123/4885SMN1; SMN2 4185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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