SCHEMBL16425791

SCHEMBL16425791

C=CC(=O)OCCCCOc1ccc(C(=O)Oc2ccc(-c3ncc(CCCCCCCCCC)cn3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.53
▸ SMN1; SMN2 Q16637 4/20 0.53
▸ RARB P10826 4/20 0.53
▸ NPC1 O15118 3/20 0.52
▸ LMNA P02545 3/20 0.52
▸ NFKB1 P19838 3/20 0.52
▸ NFKB2 Q00653 3/20 0.52
▸ RELA Q04206 3/20 0.52
▸ THRB P10828 2/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ CYP2D6 P10635 1/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ KMT2A Q03164 3/20 0.48
▸ MEN1 O00255 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4332257 0.95 RARB (0.58) MAPTSMN1; SMN2RARBNPC1LMNA
SCHEMBL16425801 0.90 THRB (0.60) MAPTSMN1; SMN2RARBNPC1LMNA
SCHEMBL10018716 0.90 THRB (0.60) MAPTSMN1; SMN2RARBNPC1LMNA
SCHEMBL13927210 0.90 THRB (0.60) MAPTSMN1; SMN2RARBNPC1LMNA
SCHEMBL9996704 0.90 THRB (0.60) MAPTSMN1; SMN2RARBNPC1LMNA
SCHEMBL9817443 0.90 RARB (0.64) MAPTSMN1; SMN2RARBNPC1LMNA
SCHEMBL11193052 0.90 RARB (0.64) MAPTSMN1; SMN2RARBNPC1LMNA
SCHEMBL4332253 0.90 MAPT (0.46) MAPTSMN1; SMN2RARBNPC1LMNA
SCHEMBL9722126 0.90 MAPT (0.68) MAPTSMN1; SMN2NPC1LMNANFKB1
SCHEMBL9722325 0.90 MAPT (0.68) MAPTSMN1; SMN2NPC1LMNANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9383491-B2 Retardation film, polarizing plate, and liquid crystal display FUJIFILM CORPORATION (JP) 2016-07-05 — — US disclosed
US-9383491-B2 Retardation film, polarizing plate, and liquid crystal display FUJIFILM CORPORATION (JP) 2016-07-05 — — US disclosed
US-20160131809-A1 PHASE DIFFERENCE FILM, POLARIZATION PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-05-12 — — US disclosed
US-20160131809-A1 PHASE DIFFERENCE FILM, POLARIZATION PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-05-12 — — US disclosed
US-20150029445-A1 RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2015-01-29 — — US disclosed
US-20150029445-A1 RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2015-01-29 — — US disclosed
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