Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604823 | 1.00 | HPGD (0.35) | HPGDRAB9APOLBNCEH1PTPN1 | |
| SCHEMBL795688 | 0.81 | MEN1 (0.39) | HPGDALDH1A1TDP1HTTMEN1 | |
| SCHEMBL795689 | 0.81 | MEN1 (0.39) | HPGDALDH1A1TDP1HTTMEN1 | |
| SCHEMBL7104073 | 0.78 | ALDH1A1 (0.41) | HPGDPOLBALDH1A1TDP1HTT | |
| SCHEMBL7104075 | 0.78 | ALDH1A1 (0.41) | HPGDPOLBALDH1A1TDP1HTT | |
| SCHEMBL5147274 | 0.76 | HPGD (0.38) | HPGDRAB9APOLBNCEH1MDM2 | |
| SCHEMBL5148279 | 0.76 | ALDH1A1 (0.44) | HPGDRAB9APOLBNCEH1MDM2 | |
| SCHEMBL6513683 | 0.74 | HPGD (0.42) | HPGDPOLBNCEH1ALDH1A1MEN1 | |
| SCHEMBL6884210 | 0.74 | HPGD (0.37) | HPGDRAB9APOLBNCEH1MDM2 | |
| SCHEMBL6513679 | 0.74 | HPGD (0.42) | HPGDPOLBNCEH1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115887-A4 | PARALLEL SELEX | INVENUX INC (US) | 2002-07-17 | — | — | EP | disclosed |
| EP-1115887-A1 | PARALLEL SELEX | Invenux, Inc. (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017398-A1 | PARALLEL SELEX | INVENUX, INC. (US) | 2000-03-30 | — | — | WO | disclosed |