Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104075 | 1.00 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPTHPGDPTGDR2 | |
| SCHEMBL7104071 | 0.91 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPTHPGDPTGDR2 | |
| SCHEMBL7603982 | 0.81 | MEN1 (0.46) | ALDH1A1MAPTHPGDPTGDR2CYP1A2 | |
| SCHEMBL7603981 | 0.81 | MEN1 (0.46) | ALDH1A1MAPTHPGDPTGDR2CYP1A2 | |
| SCHEMBL28102381 | 0.80 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTHPGDPTGDR2 | |
| Ethane SCHEMBL668960 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTHPGDPTGDR2 | |
| SCHEMBL32662599 | 0.79 | CYP1A2 (0.46) | ALDH1A1SMN1; SMN2MAPTHPGDPTGDR2 | |
| SCHEMBL7604820 | 0.78 | HPGD (0.35) | ALDH1A1MAPTHPGDCYP1A2MEN1 | |
| SCHEMBL7604823 | 0.78 | HPGD (0.35) | ALDH1A1MAPTHPGDCYP1A2MEN1 | |
| SCHEMBL8391721 | 0.78 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPTHPGDPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030099945-A1 | Parallel selex | INVENUX, INC. (US) | 2003-05-29 | — | — | US | disclosed |
| US-6048698-A | PRODUCING PRODUCTS BY BOND FORMATION OF A REACTANT BOUND TO NUCLEIC ACID AND A FREE REACTANT, THEN CONTACTING PRODUCT LIBRARY WITH TARGET TO PARTITION PRODUCTS BY ABILITY TO PERFORM PRESELECTED FUNCTION | NEXSTAR PHARMACEUTICALS, INC. (US) | 2000-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030099945-A1 | Parallel selex | SELE, MTREX, NSUN3 | ALDH1A1 1312/4885SMN1; SMN2 723/4885MAPT 3383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.