SCHEMBL7604822

SCHEMBL7604822

O=C=Nc1ccc(Oc2ccccc2-c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.57
NCOA3 Q9Y6Q9 1/20 0.57
PTGS2 P35354 1/20 0.47
FFAR4 Q5NUL3 2/20 0.45
FFAR1 O14842 1/20 0.43
AR P10275 1/20 0.43
BRD4 O60885 4/20 0.41
SCN9A Q15858 2/20 0.41
GSTP1 P09211 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 2/20 0.37
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TP53 P04637 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
ADRB2 P07550 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7239465 0.90 NCOA1 (0.42) NCOA1NCOA3PTGS2FFAR4BRD4
SCHEMBL6940624 0.87 NCOA1 (0.42) NCOA1NCOA3PTGS2FFAR4FFAR1
SCHEMBL3317595 0.80 CYP3A4 (0.43) NCOA1NCOA3PTGS2FFAR4BRD4
SCHEMBL242048 0.79 LTA4H (0.50) GSTP1TSHRCYP3A4
SCHEMBL29812870 0.79 CYP3A4 (0.40) LMNAGAAKMT2ATSHRCYP3A4
SCHEMBL1071989 0.79 CYP3A4 (0.40) LMNAGAAKMT2ATSHRCYP3A4
SCHEMBL11337528 0.79 NCOA1 (0.62) NCOA1NCOA3PTGS2FFAR4FFAR1
SCHEMBL9208935 0.77 NCOA1 (0.75) NCOA1NCOA3PTGS2FFAR4FFAR1
SCHEMBL1958156 0.77 NCOA1 (0.74) NCOA1NCOA3PTGS2FFAR4FFAR1
SCHEMBL50333 0.75 CYP3A4 (0.54) KMT2ATSHRCYP3A4TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020115869-A1 Lambda-shaped carbazole and main-chain NLO polyurethane containing the same NATIONAL SCIENCE COUNCIL (TW) 2002-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115869-A1 Lambda-shaped carbazole and main-chain NLO polyurethane containing the same POLL, POLK, LBR NCOA1 1762/4885NCOA3 755/4885PTGS2 976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.