SCHEMBL760536

SCHEMBL760536

CC(O)C1CCC(CO)CC1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.35
ESR1 P03372 6/20 0.34
ESR2 Q92731 6/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2C9 P11712 2/20 0.34
TDP1 Q9NUW8 1/20 0.32
SHBG P04278 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17219538 0.93 ESR1 (0.31) APLNRESR1ESR2CYP3A4CYP2C9
SCHEMBL2294170 0.84 APLNR (0.35) APLNRESR1ESR2CYP3A4CYP2C9
SCHEMBL225662 0.84 APLNR (0.35) APLNRESR1ESR2CYP3A4CYP2C9
SCHEMBL9815797 0.84 APLNR (0.35) APLNRESR1ESR2CYP3A4CYP2C9
SCHEMBL158458 0.84 APLNR (0.35) APLNRESR1ESR2CYP3A4CYP2C9
SCHEMBL9177731 0.83 APLNR (0.38) APLNRESR1ESR2CYP3A4CYP2C9
SCHEMBL21433162 0.83 TP53 (0.41) SHBG
SCHEMBL127724 0.83
SCHEMBL5444346 0.83
SCHEMBL240851 0.83 ALDH1A1 (0.36) TDP1SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567678-B1 PROCESS FOR TANNING AND TANNING AGENT TFL LEDERTECHNIK GMBH (DE) 2012-03-21 EP disclosed
EP-1567678-A1 PROCESS FOR TANNING AND TANNING AGENT TFL Ledertechnik GmbH (DE) 2005-08-31 EP disclosed
WO-2004053170-A1 PROCESS FOR TANNING AND TANNING AGENT TFL LEDERTECHNIK GMBH (DE) 2004-06-24 WO disclosed