Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 4/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222126 | 0.81 | ACACA (0.64) | ACACAEGFRKDM4EALDH1A1HPGD | |
| SCHEMBL22406023 | 0.80 | METAP2 (0.41) | ACACAGRM2EGFRKDM4EALDH1A1 | |
| SCHEMBL29399315 | 0.79 | ACACA (0.72) | ACACAEGFRKDM4EALDH1A1HPGD | |
| SCHEMBL1042853 | 0.79 | ACACA (0.72) | ACACAEGFRKDM4EALDH1A1HPGD | |
| SCHEMBL28251705 | 0.78 | TOP1 (0.66) | ACACAGRM2KDM4EALDH1A1HPGD | |
| SCHEMBL7611160 | 0.78 | TOP1 (0.66) | ACACAGRM2KDM4EALDH1A1HPGD | |
| SCHEMBL29397116 | 0.78 | TOP1 (0.66) | ACACAGRM2KDM4EALDH1A1HPGD | |
| SCHEMBL7610922 | 0.78 | ACACA (0.53) | ACACAGRM2EGFRKDM4EALDH1A1 | |
| SCHEMBL669466 | 0.78 | ACACA (0.65) | ACACAEGFRKDM4EALDH1A1HPGD | |
| SCHEMBL16990162 | 0.78 | ACACA (0.70) | ACACAEGFRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198806-A | Method for synthesizing quinoline by aromatic amine and diketone | UNIV NANYANG NORMAL | 2015-12-30 | — | — | CN | claimed |
| CN-105198806-A | Method for synthesizing quinoline by aromatic amine and diketone | UNIV NANYANG NORMAL | 2015-12-30 | — | — | CN | disclosed |
| US-20020151659-A1 | Formed from 6,6'-bis(2-(4-fluorophenyl)-4- phenylquinoline) and 4,4'-(1,1,1,3,3,3-hexafluoro-2,2-propylidene)bisphenol and 2,2-bis((4-maleimidophenoxy)phenyl)propane; dielectrics | HITACHI CHEMICAL CO., LTD. (JP) | 2002-10-17 | — | — | US | disclosed |