SCHEMBL760569

SCHEMBL760569

O=C1N=C(N(OCCc2cnc(Cl)c(Cl)c2)c2ccccc2)CO1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.32
MAOB P27338 3/20 0.32
KMT2A Q03164 2/20 0.30
MEN1 O00255 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231698 0.74 ALDH1A1 (0.33) MAOB
SCHEMBL230357 0.73 MAOA (0.33) MAOAMAOB
SCHEMBL760570 0.73 TDP1 (0.31)
SCHEMBL232213 0.71 ALDH1A1 (0.37)
SCHEMBL232437 0.69
SCHEMBL232691 0.69 ALDH1A1 (0.32)
SCHEMBL229097 0.68 AR (0.34)
SCHEMBL765378 0.68 TDP1 (0.30)
SCHEMBL765379 0.67
SCHEMBL230085 0.61 ALDH1A1 (0.37) KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2587922-A1 IMPROVED INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES Bayer Intellectual Property GmbH (DE) 2013-05-08 EP disclosed
WO-2012000902-A1 IMPROVED INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES BAYER CROPSCIENCE AG (DE) 2012-01-05 WO disclosed