Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.60 |
| ▸ | CDC25B | P30305 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | CDC25A | P30304 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.48 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555840 | 0.83 | BACE1 (0.75) | BACE1CDC25BMEN1KMT2ALMNA | |
| SCHEMBL7599132 | 0.79 | BACE1 (0.55) | BACE1CDC25BMEN1KMT2ALMNA | |
| SCHEMBL30174331 | 0.78 | KDR (0.53) | BACE1CDC25BMEN1KMT2ALMNA | |
| SCHEMBL8666417 | 0.78 | KDR (0.53) | BACE1CDC25BMEN1KMT2ALMNA | |
| SCHEMBL29673492 | 0.75 | BACE1 (1.00) | BACE1CDC25BMEN1KMT2ALMNA | |
| SCHEMBL8596446 | 0.75 | PTPN1 (0.64) | BACE1CDC25BMEN1KMT2ALMNA | |
| SCHEMBL5485068 | 0.75 | BACE1 (1.00) | BACE1CDC25BMEN1KMT2ALMNA | |
| SCHEMBL9286666 | 0.73 | BACE1 (0.60) | BACE1CDC25BMEN1KMT2ALMNA | |
| SCHEMBL1708066 | 0.73 | BACE1 (0.60) | BACE1CDC25BMEN1KMT2ALMNA | |
| SCHEMBL28564373 | 0.72 | BACE1 (0.60) | BACE1CDC25BMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861830-B1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | OREAL (FR) | 2002-12-18 | — | — | EP | disclosed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | disclosed |
| EP-0861830-A1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | L'OREAL (FR) | 1998-09-02 | — | — | EP | disclosed |