Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 7/20 | 0.56 |
| ▸ | MTTP | P55157 | 7/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609278 | 0.91 | ALDH1A1 (0.58) | APOBMTTPEPHX2RXFP1 | |
| SCHEMBL7609224 | 0.88 | APOB (0.54) | APOBMTTPEPHX2TRPV4RXFP1 | |
| SCHEMBL7608643 | 0.87 | APOB (0.55) | APOBMTTPEPHX2RXFP1KCNK3 | |
| SCHEMBL7605756 | 0.87 | APOB (0.57) | APOBMTTPEPHX2RXFP1KCNK3 | |
| SCHEMBL7611600 | 0.87 | EPHX2 (0.52) | APOBMTTPEPHX2TRPV4RXFP1 | |
| SCHEMBL7611015 | 0.86 | MTTP (0.54) | APOBMTTPEPHX2 | |
| SCHEMBL7607440 | 0.86 | MTTP (0.57) | APOBMTTP | |
| SCHEMBL7605815 | 0.85 | APOB (0.63) | APOBMTTPRXFP1KCNK3 | |
| SCHEMBL7610500 | 0.85 | APOB (0.51) | APOBMTTPEPHX2TRPV4RXFP1 | |
| SCHEMBL7612180 | 0.85 | MTTP (0.61) | APOBMTTPRXFP1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | APOB 45/4885MTTP 1/4885EPHX2 1348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.