SCHEMBL76058

SCHEMBL76058

C=CC(=O)Oc1ccc(-c2ccc(C(=O)OC(C)CCCCCC)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 6/20 0.51
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.46
RARB P10826 4/20 0.42
THRA P10827 4/20 0.42
MGLL Q99685 1/20 0.42
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PNLIP P16233 1/20 0.39
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
FAAH O00519 1/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14370092 0.90 THRB (0.49) THRBALDH1A1TSHRRARBNPC1
SCHEMBL6872611 0.89 ALDH1A1 (0.52) THRBALDH1A1TSHRRARBMGLL
SCHEMBL6872017 0.89 ALDH1A1 (0.52) THRBALDH1A1TSHRRARBMGLL
SCHEMBL13828468 0.89 THRB (0.49) THRBALDH1A1RARBTHRAMGLL
SCHEMBL6872703 0.88 TSHR (0.51) THRBALDH1A1TSHRRARBMGLL
SCHEMBL9296056 0.87 ALDH1A1 (0.50) ALDH1A1TSHRRARBMGLLNFKB1
SCHEMBL6871505 0.87 ALDH1A1 (0.50) ALDH1A1TSHRRARBMGLLNFKB1
SCHEMBL7129914 0.86 ALDH1A1 (0.59) ALDH1A1TSHRRARBNPC1PDCD1
SCHEMBL7131644 0.86 ALDH1A1 (0.59) ALDH1A1TSHRRARBNPC1PDCD1
SCHEMBL14273580 0.86 ALDH1A1 (0.59) ALDH1A1TSHRRARBNPC1PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8992796-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2015-03-31 US disclosed
US-8992796-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2015-03-31 US disclosed
US-8139189-B2 Liquid crystal display having particular oblique vapor deposition-alignment layer with ferroelectric liquid crystal DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-20 US disclosed
US-20120056129-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2012-03-08 US disclosed
US-8130358-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-06 US disclosed
US-8094269-B2 Liquid crystal display device, manufacturing method thereof, and color filter substrate HITACHI DISPLAYS, LTD. (JP) 2012-01-10 US disclosed
US-7892449-B2 Liquid crystal display and manufacturing method of same DAI NIPPON PRINTING CO., LTD. (JP) 2011-02-22 US disclosed
US-7871540-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2011-01-18 US disclosed
US-7812905-B2 Liquid crystal display device and manufacturing method thereof HITACHI DISPLAYS, LTD. (JP) 2010-10-12 US disclosed
US-7683203-B2 Polymerizable compound and composition containing the polymerizable compound ADEKA CORPORATION (JP) 2010-03-23 US disclosed
US-20100053525-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-03-04 US disclosed
US-20100007832-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-01-14 US disclosed
US-7570331-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-04 US disclosed
US-7499135-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-03-03 US disclosed
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2009-02-26 US disclosed
US-20090021675-A1 Liquid Crystal Display Device, Manufacturing Method Thereof, and Color Filter Substrate IPS ALPHA SUPPORT CO., LTD. (JP) 2009-01-22 US disclosed
US-20080291377-A1 Liquid Crystal Display Device and Manufacturing Method Thereof HITACHI DISPLAYS, LTD. (JP) 2008-11-27 US disclosed
US-20080074588-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF MAGNOLIA PURPLE CORPORATION (JP) 2008-03-27 US disclosed
US-20070026165-A1 Liquid crystal display and manufacturing method of same DAI NIPPON PRINTING CO., LTD. (JP) 2007-02-01 US disclosed
US-20070026165-A1 Liquid crystal display and manufacturing method of same DAI NIPPON PRINTING CO., LTD. (JP) 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION H1-0, H1-4, H1-10 THRB 3657/4885ALDH1A1 4147/4885TSHR 1470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.