Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | KLK7 | P49862 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518810 | 0.76 | L3MBTL1 (0.44) | KDM4EKLK7ALDH1A1SMN1; SMN2RIPK1 | |
| SCHEMBL7518808 | 0.76 | L3MBTL1 (0.44) | KDM4EKLK7ALDH1A1SMN1; SMN2RIPK1 | |
| SCHEMBL30872986 | 0.76 | RIPK1 (0.53) | KDM4EKLK7ALDH1A1SMN1; SMN2PPIB | |
| SCHEMBL29375243 | 0.74 | KDM4E (0.60) | KDM4EKLK7ALDH1A1SMN1; SMN2PPIB | |
| SCHEMBL6086511 | 0.74 | KDM4E (0.65) | KDM4EKLK7ALDH1A1SMN1; SMN2PPIB | |
| SCHEMBL7605816 | 0.71 | EDNRA (0.42) | KDM4EKLK7ALDH1A1SMN1; SMN2PPIB | |
| SCHEMBL21159521 | 0.71 | KDM4E (0.56) | KDM4EKLK7ALDH1A1SMN1; SMN2PPIB | |
| SCHEMBL620146 | 0.70 | KDM4E (0.63) | KDM4EKLK7ALDH1A1SMN1; SMN2PPIB | |
| SCHEMBL23957129 | 0.69 | KDM4E (0.57) | KDM4EKLK7ALDH1A1SMN1; SMN2PPIB | |
| SCHEMBL9444279 | 0.69 | KDM4E (0.68) | KDM4EKLK7ALDH1A1SMN1; SMN2PPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915864-B1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARM CO LTD (KR) | 2002-09-04 | — | — | EP | disclosed |