SCHEMBL7605833

SCHEMBL7605833

O=C1C=CC(=O)N1c1ccc(Oc2ccc(C(c3ccc(Oc4ccc(N5C(=O)C=CC5=O)cc4C(F)(F)F)cc3)(C(F)(F)F)C(F)(F)F)cc2)c(C(F)(F)F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 7/20 0.41
HSP90AA1 P07900 2/20 0.38
LMNA P02545 2/20 0.38
ATM Q13315 2/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
PKM P14618 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
CCR6 P51684 1/20 0.38
KMT2A Q03164 1/20 0.38
G6PD P11413 1/20 0.36
TLR9 Q9NR96 1/20 0.36
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
FAAH O00519 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
RAB9A P51151 1/20 0.34
NR3C1 P04150 1/20 0.33
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30793053 1.00 MGLL (0.41) MGLLHSP90AA1LMNAATMMEN1
SCHEMBL8729999 0.93 MGLL (0.44) MGLLHSP90AA1LMNAATMMEN1
SCHEMBL30793023 0.91 MGLL (0.49) MGLLHSP90AA1LMNAATMMEN1
SCHEMBL29191799 0.89 MGLL (0.40) MGLLHSP90AA1LMNAATMMEN1
SCHEMBL28221672 0.88 MGLL (0.41) MGLLHSP90AA1LMNAATMMEN1
SCHEMBL29191798 0.86 TLR9 (0.43) MGLLHSP90AA1LMNAATMMEN1
SCHEMBL30793038 0.86 TLR9 (0.43) MGLLHSP90AA1LMNAATMMEN1
SCHEMBL27819277 0.84 MGLL (0.56) MGLLHSP90AA1LMNAATMMEN1
SCHEMBL8730168 0.82 MGLL (0.44) MGLLHSP90AA1LMNAATMMEN1
SCHEMBL94319 0.82 MGLL (0.60) MGLLHSP90AA1LMNAATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN claimed
EP-0449292-B1 Multilayer printed circuit board and production thereof HITACHI LTD (JP) 1997-08-20 EP claimed
US-5478918-A Low stress polyimide composition and precursor composition solution of same CENTRAL GLASS COMPANY, LIMITED (JP) 1995-12-26 US claimed
JP-2085238-A None JP disclosed
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN disclosed
US-20020151659-A1 Formed from 6,6'-bis(2-(4-fluorophenyl)-4- phenylquinoline) and 4,4'-(1,1,1,3,3,3-hexafluoro-2,2-propylidene)bisphenol and 2,2-bis((4-maleimidophenoxy)phenyl)propane; dielectrics HITACHI CHEMICAL CO., LTD. (JP) 2002-10-17 US disclosed
US-6462148-B1 RESIN COMPOSITION COMPRISING A POLYMER CONTAINING A QUINOLINE RING AND A THERMOSETTING RESIN, AN INSULATING MATERIAL CONSTITUTED BY SAID RESIN COMPOSITION AND AN ADHESIVE FILM, PARTICULARLY A RESIN FOR AN INTERLAYER INSULATION FILM HITACHI CHEMICAL CO., LTD. (JP) 2002-10-08 US disclosed
EP-0449292-B1 Multilayer printed circuit board and production thereof HITACHI LTD (JP) 1997-08-20 EP disclosed
EP-0364785-B1 Thermosetting resin composition, printed circuit board using the resin composition and process for producing printed circuit board HITACHI LTD (JP) 1995-03-01 EP disclosed
US-5352762-A Fluorine-containing biscyanamide thermosetting resin, heat resistance, adhesion HITACHI, LTD. (JP) 1994-10-04 US disclosed
US-5194518-A Polyimides, prepregs, fluoropolymers NITTO DENKO CORPORATION (JP) 1993-03-16 US disclosed
US-5098971-A Heat resistant molding materials for wiring boards and insulation layers HITACHI, LTD. (JP) 1992-03-24 US disclosed
US-5089628-A Heat resistance, moisture resistance, low dielectric constants CENTRAL GLASS COMPANY, LIMITED (JP) 1992-02-18 US disclosed
EP-0449292-A2 Multilayer printed circuit board and production thereof HITACHI, LTD. (JP) 1991-10-02 EP disclosed
US-5045381-A Containing (iso)cyanate compound and poly(p-hydroxystyrene) derivative HITACHI, LTD. (JP) 1991-09-03 US disclosed
EP-0422379-A2 Thermosetting resin composition, resin sheet, prepreg and laminated sheet NITTO DENKO CORPORATION (JP) 1991-04-17 EP disclosed
EP-0364785-A1 Thermosetting resin composition, printed circuit board using the resin composition and process for producing printed circuit board HITACHI, LTD. (JP) 1990-04-25 EP disclosed
JP-H0285238-A FLUORINE-CONTAINING BISMALEAMIC ACID AND BISMALEIMIDE CENTRAL GLASS CO LTD 1990-03-26 JP disclosed