SCHEMBL7605909

SCHEMBL7605909

CN(C(=O)NC(=O)c1c(Cl)cccc1Cl)c1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 6/20 0.46
POLB P06746 2/20 0.43
ALDH1A1 P00352 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
UTS2R Q9UKP6 1/20 0.41
RAB9A P51151 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
PPIA P62937 1/20 0.40
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9348899 0.89 POLB (0.51) GPBAR1POLBALDH1A1CYP3A4MAPT
SCHEMBL7607640 0.88 GPBAR1 (0.44) GPBAR1POLBALDH1A1CYP3A4RAB9A
SCHEMBL9348699 0.87 GPBAR1 (0.45) GPBAR1POLBALDH1A1UTS2RRAB9A
SCHEMBL7605858 0.86 RAB9A (0.49) GPBAR1POLBALDH1A1RAB9AGAA
SCHEMBL30499675 0.85 GPBAR1 (0.44) GPBAR1ALDH1A1CYP3A4RAB9AGAA
SCHEMBL7606197 0.85 GPBAR1 (0.44) GPBAR1ALDH1A1CYP3A4RAB9AGAA
SCHEMBL4908017 0.85 GPBAR1 (0.48) GPBAR1POLBALDH1A1TDP1CYP3A4
SCHEMBL9348957 0.84 GPBAR1 (0.47) GPBAR1POLBALDH1A1RAB9AGAA
SCHEMBL7605921 0.84 SMN1; SMN2 (0.44) POLBALDH1A1RAB9AGAAMAPT
SCHEMBL9348628 0.83 ITGB1 (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US claimed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
WO-1997045017-A1 BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-12-04 WO claimed
US-4243680-A N-(2,6-DIHALOBENZOYL)-N'-(HALOGENATED PHENYL) UREA; LARVICIDES THOMPSON-HAYWARD CHEMICAL COMPANY (US) 1981-01-06 US claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US disclosed
US-6057370-A APPLYING TO THE FOLIAGE OF SAID GENETICALLY ALTERED COTTON PLANT AN ENHANCED PESTICIDALLY ACTIVE AMOUNT OF A SUBSTITUTED BENZOYL UREA MACDERMID AGRICULTURAL SOLUTIONS, INC. 2000-05-02 US disclosed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO disclosed
US-4833151-A INTERFERES WITH METAMORPHOSES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1989-05-23 US disclosed
US-4607044-A Insecticidal use of ureas and thioureas DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1986-08-19 US disclosed
US-4243680-A N-(2,6-DIHALOBENZOYL)-N'-(HALOGENATED PHENYL) UREA; LARVICIDES THOMPSON-HAYWARD CHEMICAL COMPANY (US) 1981-01-06 US disclosed
US-4166124-A IMIDAZOLE OR PYRIMIDINE RINGS U.S. PHILIPS CORPORATION (US) 1979-08-28 US disclosed
US-4013717-A BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES U.S. PHILIPS CORPORATION (US) 1977-03-22 US disclosed
US-3989842-A Certain substituted benzoyl urea insecticides U.S. PHILIPS CORPORATION (US) 1976-11-02 US disclosed
US-3933908-A INSECTICIDE U.S. PHILIPS CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 GPBAR1 3739/4885POLB 3874/4885ALDH1A1 3840/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 GPBAR1 3739/4885POLB 3874/4885ALDH1A1 3840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.