Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372591 | 0.88 | KMT2A (0.41) | GAATLR7MEN1KMT2ATDP1 | |
| SCHEMBL14034291 | 0.87 | ESR1 (0.43) | GAATLR7MEN1KMT2ATDP1 | |
| SCHEMBL13774578 | 0.87 | MEN1 (0.47) | GPBAR1TLR7MEN1KMT2AALDH1A1 | |
| SCHEMBL9653398 | 0.87 | RORC (0.43) | GPBAR1GAATLR7MEN1KMT2A | |
| SCHEMBL7605909 | 0.85 | GPBAR1 (0.46) | GPBAR1GAAPOLBALDH1A1TDP1 | |
| SCHEMBL4142624 | 0.84 | PPIA (0.40) | TLR7MEN1KMT2ATDP1 | |
| SCHEMBL10915862 | 0.84 | GAA (0.46) | GPBAR1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL9653358 | 0.82 | KMT2A (0.41) | GAATLR7MEN1KMT2AALDH1A1 | |
| SCHEMBL4636307 | 0.82 | KMT2A (0.39) | TLR7MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9652414 | 0.82 | IL2 (0.42) | GPBAR1TLR7MEN1KMT2ARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376430-B1 | APPLYING TO CROP | UNIROYAL CHEMICAL COMPANY, INC. | 2002-04-23 | — | — | US | claimed |
| WO-1999016316-A1 | ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1999-04-08 | — | — | WO | claimed |
| WO-1997045017-A1 | BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-12-04 | — | — | WO | claimed |
| US-10322118-B2 | Compounds and methods for inhibiting Cif virulence factor | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2019-06-18 | — | — | US | disclosed |
| US-20160206605-A1 | COMPOUNDS AND METHODS FOR INHIBITING CIF VIRULENCE FACTOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-07-21 | — | — | US | disclosed |
| US-20160206605-A1 | COMPOUNDS AND METHODS FOR INHIBITING CIF VIRULENCE FACTOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-07-21 | — | — | US | disclosed |
| US-20150045389-A1 | COMPOUNDS AND METHODS FOR INHIBITING CIF VIRULENCE FACTOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-02-12 | — | — | US | disclosed |
| US-20150045389-A1 | COMPOUNDS AND METHODS FOR INHIBITING CIF VIRULENCE FACTOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-02-12 | — | — | US | disclosed |
| WO-2013155047-A2 | COMPOUNDS AND METHODS FOR INHIBITING CIF VIRULENCE FACTOR | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2013-10-17 | — | — | WO | disclosed |
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-13 | — | — | US | disclosed |
| WO-1997045017-A1 | BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-12-04 | — | — | WO | disclosed |
| US-5142064-A | Larvicides has benzoyl or thiobenzoyl group | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-08-25 | — | — | US | disclosed |
| US-4920135-A | NONPHYTOTOXIC, INTERFERE WITH METAMORPHOSIS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-04-24 | — | — | US | disclosed |
| US-4833151-A | INTERFERES WITH METAMORPHOSES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-05-23 | — | — | US | disclosed |
| US-4607044-A | Insecticidal use of ureas and thioureas | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-08-19 | — | — | US | disclosed |
| US-4166124-A | IMIDAZOLE OR PYRIMIDINE RINGS | U.S. PHILIPS CORPORATION (US) | 1979-08-28 | — | — | US | disclosed |
| US-4013717-A | BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES | U.S. PHILIPS CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-3989842-A | Certain substituted benzoyl urea insecticides | U.S. PHILIPS CORPORATION (US) | 1976-11-02 | — | — | US | disclosed |
| US-3933908-A | INSECTICIDE | U.S. PHILIPS CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160206605-A1 | COMPOUNDS AND METHODS FOR INHIBITING CIF VIRULENCE FACTOR | CFTR, NCF1, CFB | GPBAR1 3178/4885GAA 1352/4885TLR7 3702/4885 |
| US-10322118-B2 | Compounds and methods for inhibiting Cif virulence factor | CFTR, NCF1, CFB | GPBAR1 3178/4885GAA 1352/4885TLR7 3702/4885 |
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | L3MBTL4, L3MBTL3, L3MBTL1 | GPBAR1 3250/4885GAA 3960/4885TLR7 1638/4885 |
| US-20150045389-A1 | COMPOUNDS AND METHODS FOR INHIBITING CIF VIRULENCE FACTOR | CFTR, NCF1, CFB | GPBAR1 3224/4885GAA 1517/4885TLR7 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.