Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | NOS2 | P35228 | 4/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332207 | 0.76 | NOS2 (0.52) | SLC6A4CYP2D6SLC6A2NOS2BCL2A1 | |
| SCHEMBL7604218 | 0.72 | SLC6A4 (0.41) | SLC6A4CYP2D6SLC6A2NOS2BCL2A1 | |
| Oxalic Acid SCHEMBL6337578 | 0.72 | CYP2D6 (0.53) | SLC6A4CYP2D6SLC6A2NOS2BCL2A1 | |
| SCHEMBL6980102 | 0.70 | CYP2D6 (0.43) | SLC6A4CYP2D6SLC6A2NOS2BCL2A1 | |
| SCHEMBL6329018 | 0.69 | SLC6A4 (0.70) | SLC6A4CYP2D6SLC6A2NOS2BCL2A1 | |
| SCHEMBL6503271 | 0.69 | SLC6A4 (0.72) | SLC6A4CYP2D6SLC6A2NOS2 | |
| Hydrochloric Acid SCHEMBL6328545 | 0.68 | SLC6A4 (0.71) | SLC6A4CYP2D6SLC6A2NOS2BCL2A1 | |
| SCHEMBL21691198 | 0.68 | CYP2D6 (0.48) | SLC6A4CYP2D6SLC6A2NOS2BCL2A1 | |
| SCHEMBL31376036 | 0.68 | CYP2D6 (0.48) | SLC6A4CYP2D6SLC6A2NOS2BCL2A1 | |
| Oxalic Acid SCHEMBL7665481 | 0.67 | CYP2D6 (0.42) | SLC6A4CYP2D6SLC6A2NOS2BCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263715-A1 | NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES | AstraZeneca AB (SE) | 2002-12-11 | — | — | EP | claimed |
| WO-2001062714-A1 | NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | claimed |
| EP-1263715-A1 | NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES | AstraZeneca AB (SE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062714-A1 | NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | disclosed |