Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604027 | 0.89 | PTGS2 (0.38) | PTGS2PTGES | |
| SCHEMBL7606107 | 0.88 | KMT2A (0.44) | PTGS2PTGES | |
| SCHEMBL1178147 | 0.87 | PTGS2 (0.39) | PTGS2PTGES | |
| SCHEMBL1178375 | 0.84 | PTGS2 (0.42) | PTGS2PTGES | |
| SCHEMBL1083289 | 0.83 | PTGS2 (0.38) | PTGS2PTGES | |
| SCHEMBL7605922 | 0.83 | KMT2A (0.42) | PTGS2PTGES | |
| SCHEMBL12872156 | 0.82 | PTGES (0.39) | PTGS2PTGES | |
| SCHEMBL1177915 | 0.81 | PTGES (0.40) | PTGS2PTGES | |
| SCHEMBL1178784 | 0.80 | PTGS2 (0.40) | PTGS2PTGES | |
| SCHEMBL1178098 | 0.80 | PTGS2 (0.37) | PTGS2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |