Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.38 |
| ▸ | CFD | P00746 | 2/20 | 0.35 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606209 | 0.80 | VDR (0.42) | VDRPTGS2ACMSDPRKCIFFAR1 | |
| SCHEMBL7615200 | 0.75 | VDR (0.52) | VDR | |
| SCHEMBL7606363 | 0.75 | VDR (0.43) | VDRFFAR1 | |
| SCHEMBL7608506 | 0.72 | LTB4R (0.34) | VDRPTGS2FFAR1 | |
| SCHEMBL7610502 | 0.71 | VDR (0.42) | VDRPTGS2FFAR1 | |
| SCHEMBL7606369 | 0.71 | FFAR1 (0.43) | VDRFFAR1 | |
| SCHEMBL7647798 | 0.71 | VDR (0.39) | VDR | |
| SCHEMBL6564902 | 0.71 | VDR (0.55) | VDRACMSDPRKCIFFAR1 | |
| SCHEMBL6756665 | 0.71 | VDR (0.47) | VDR | |
| SCHEMBL7608523 | 0.71 | VDR (0.41) | VDRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | claimed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | claimed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |