SCHEMBL7606252

SCHEMBL7606252

Brc1cccc2c1-c1ccccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
MAPK1 P28482 3/20 0.46
MAPT P10636 4/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
POLB P06746 3/20 0.43
MEN1 O00255 2/20 0.43
HTT P42858 2/20 0.43
KMT2A Q03164 2/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
PDK2 Q15119 1/20 0.42
HKDC1 Q2TB90 1/20 0.42
PTPRC P08575 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TSHR P16473 1/20 0.38
ATM Q13315 1/20 0.38
LMNA P02545 3/20 0.35
NPC1 O15118 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19237177 1.00 ALDH1A1 (0.46) ALDH1A1MAPK1MAPTL3MBTL1POLB
SCHEMBL31713020 0.85 CA1 (0.48) ALDH1A1MAPK1MAPTL3MBTL1POLB
SCHEMBL29124878 0.82 ALDH1A1 (0.46) ALDH1A1MAPK1MAPTL3MBTL1POLB
SCHEMBL22182094 0.82 ALDH1A1 (0.41) ALDH1A1MAPK1MAPTL3MBTL1POLB
SCHEMBL5055109 0.80 MAPT (0.57) ALDH1A1MAPK1MAPTL3MBTL1POLB
SCHEMBL29679284 0.80 PTPRC (0.57) ALDH1A1MAPK1MAPTL3MBTL1POLB
SCHEMBL20123135 0.80 ALDH1A1 (0.39) ALDH1A1MAPK1MAPTL3MBTL1POLB
SCHEMBL29403074 0.80 MAPT (0.57) ALDH1A1MAPK1MAPTL3MBTL1POLB
SCHEMBL2079031 0.80 PTPRC (0.57) ALDH1A1MAPK1MAPTL3MBTL1POLB
SCHEMBL27712873 0.80 PTPRC (0.59) ALDH1A1MAPK1MAPTL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257260-A1 Process for the hydrogenation treatment of mineral oils contaminated by chlorobiphenyls VEBA OEL Technologie und Automatisierung GmbH (DE) 1988-03-02 EP claimed
US-20240373742-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-11-07 US disclosed
CN-118834226-A Organic electroluminescent material and device 环球展览公司 2024-10-25 CN disclosed
US-20020022151-A1 Organic electroluminescent device NEC CORPORATION (JP) 2002-02-21 US disclosed
EP-0721933-B1 1,4-Disubstituted 2,6-difluorobenzene compounds and liquid crystal media MERCK PATENT GMBH (DE) 1999-07-07 EP disclosed
EP-0462237-B1 1,2-DISUBSTITUTED 2,6-DIFLUOROBENZENE COMPOUNDS AND LIQUID CRYSTAL MEDIA MERCK PATENT GMBH (DE) 1997-03-12 EP disclosed
EP-0721933-A1 1,4-Disubstituted 2,6-difluorobenzene compounds and liquid crystal media MERCK PATENT GmbH (DE) 1996-07-17 EP disclosed
EP-0462237-A1 1,2-DISUBSTITUTED 2,6-DIFLUOROBENZENE COMPOUNDS AND LIQUID CRYSTAL MEDIA. MERCK PATENT GMBH (DE) 1991-12-27 EP disclosed
EP-0113252-B1 PROCESS FOR PRODUCING BLOCK COPOLYAMIDE TORAY INDUSTRIES, INC. (JP) 1991-08-07 EP disclosed
WO-1991008184-A2 1,2-DISUBSTITUTED 2,6-DIFLUOROBENZENE COMPOUNDS AND LIQUID CRYSTAL MEDIA MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-06-13 WO disclosed
WO-1989003812-A1 CROSS COUPLING OF TITANIUM ORGANYLS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-05-05 WO disclosed
EP-0282542-A1 PROCESS FOR THE PRODUCTION OF ALKYLENE OR CYCLICALLY LINKED COMPOUNDS. MERCK PATENT GMBH (DE) 1988-09-21 EP disclosed
WO-1988002357-A2 PROCESS FOR THE PRODUCTION OF ALKYLENE OR CYCLICALLY LINKED COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-04-07 WO disclosed
EP-0257260-A1 Process for the hydrogenation treatment of mineral oils contaminated by chlorobiphenyls VEBA OEL Technologie und Automatisierung GmbH (DE) 1988-03-02 EP disclosed
EP-0257260-A1 Process for the hydrogenation treatment of mineral oils contaminated by chlorobiphenyls VEBA OEL Technologie und Automatisierung GmbH (DE) 1988-03-02 EP disclosed
US-4507465-A IMPACT STRENGTH TORAY INDUSTRIES, INC. (JP) 1985-03-26 US disclosed
EP-0113252-A2 Process for producing block copolyamide TORAY INDUSTRIES, INC. (JP) 1984-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240373742-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 ALDH1A1 526/4885MAPK1 4452/4885MAPT 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.