Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29679284 | 1.00 | PTPRC (0.57) | PTPRCADORA2AMAPTALDH1A1MEN1 | |
| SCHEMBL472644 | 0.91 | ADORA2A (0.57) | PTPRCADORA2AMAPTALDH1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL27798139 | 0.89 | ADORA2A (0.55) | PTPRCADORA2AMAPTALDH1A1MEN1 | |
| Methane SCHEMBL4593466 | 0.89 | ADORA2A (0.55) | PTPRCADORA2AMAPTALDH1A1MEN1 | |
| SCHEMBL15678555 | 0.88 | CA1 (0.52) | PTPRCADORA2AMAPTALDH1A1MEN1 | |
| SCHEMBL5412322 | 0.86 | MAPT (0.54) | PTPRCADORA2AMAPTALDH1A1MEN1 | |
| Methylamine SCHEMBL9597386 | 0.85 | ADORA2A (0.57) | PTPRCADORA2AMAPTALDH1A1MEN1 | |
| SCHEMBL6904504 | 0.83 | MAOA (0.52) | PTPRCADORA2AMAPTALDH1A1MEN1 | |
| SCHEMBL1325322 | 0.82 | PTPRC (0.58) | PTPRCADORA2AMAPTALDH1A1MEN1 | |
| SCHEMBL17852136 | 0.82 | ALDH1A1 (0.44) | PTPRCADORA2AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863694-A | A method of synthesis 9,9`- spirobifluorene derivative | 新乡市润宇新材料科技有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-105237379-A | Production method for 4-bromo fluorenone | INST CHEMISTRY CO LTD HENAN ACADEMY OF SCIENCES | 2016-01-13 | — | — | CN | claimed |
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMA INC (US) | 2026-03-05 | — | — | US | disclosed |
| US-12486230-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2025-12-02 | — | — | US | disclosed |
| US-20250282709-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2025-09-11 | — | — | US | disclosed |
| CN-115141173-B | Compound and organic electroluminescent device comprising the same | 浙江虹舞科技有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-112654613-B | Condensed-cyclic compound and organic light-emitting device comprising same | 株式会社LG化学 | 2025-02-07 | — | — | CN | disclosed |
| US-12167685-B2 | Organic compounds and organic light emitting display device using the same | LG DISPLAY CO., LTD. (KR) | 2024-12-10 | — | — | US | disclosed |
| CN-118812412-A | Preparation method of spirotrienone and coumarin and derivatives thereof | 黄淮学院 | 2024-10-22 | — | — | CN | disclosed |
| EP-4438693-A2 | HETEROCYCLIC SPIRO COMPOUNDS | Merck Patent GmbH (DE) | 2024-10-02 | — | — | EP | disclosed |
| EP-3708634-B1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2024-08-14 | — | — | EP | disclosed |
| US-20100130503-A1 | NEW FLUORENE DERIVATIVES, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF AS INHIBITORS OF THE PROTEIN CHAPERONE HSP 90 | SANOFI-AVENTIS (FR) | 2010-05-27 | — | — | US | disclosed |
| US-20100130503-A1 | NEW FLUORENE DERIVATIVES, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF AS INHIBITORS OF THE PROTEIN CHAPERONE HSP 90 | SANOFI-AVENTIS (FR) | 2010-05-27 | — | — | US | disclosed |
| US-7674795-B2 | Fluorene derivatives, composition containing said derivatives and the use thereof | AVENTIS PHARMA SA (FR) | 2010-03-09 | — | — | US | disclosed |
| EP-2078009-A1 | NEW FLUORENE DERIVATIVES, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF AS INHIBITORS OF THE PROTEIN CHAPERONE HSP 90 | Sanofi-Aventis (FR) | 2009-07-15 | — | — | EP | disclosed |
| US-20080153837-A1 | Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
| WO-2008049994-A1 | NEW FLUORENE DERIVATIVES, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF AS INHIBITORS OF THE PROTEIN CHAPERONE HSP 90 | SANOFI-AVENTIS (FR) | 2008-05-02 | — | — | WO | disclosed |
| EP-1888579-A2 | NOVEL FLUORENE DERIVATIVES, COMPOSITION CONTAINING SAID DERIVATIVES AND THE USE THEREOF | Aventis Pharma S.A. (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006123061-A2 | FLUORENE DERIVATIVES, COMPOSITION CONTAINING SAID DERIVATIVES AND THE USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2006-11-23 | — | — | WO | disclosed |
| EP-0886182-A1 | Positive photoresist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | C9, SSB, C1S | PTPRC 1602/4885ADORA2A 3496/4885MAPT 1355/4885 |
| US-12486230-B2 | Materials for organic electroluminescent devices | L1CAM, EFNA1, EPCAM | PTPRC 3741/4885ADORA2A 4011/4885MAPT 1786/4885 |
| US-20100130503-A1 | NEW FLUORENE DERIVATIVES, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF AS INHIBITORS OF THE PROTEIN CHAPERONE HSP 90 | HSP90AB2P, HSPA2, HSP90AB1 | PTPRC 1524/4885ADORA2A 3671/4885MAPT 1323/4885 |
| US-20250282709-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PKD1, PIEZO1, AQP1 | PTPRC 2487/4885ADORA2A 4117/4885MAPT 2656/4885 |
| US-12167685-B2 | Organic compounds and organic light emitting display device using the same | AOX1, OCIAD1, SLCO2A1 | PTPRC 1407/4885ADORA2A 2979/4885MAPT 1420/4885 |
| US-20080153837-A1 | Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof | HSP90B1, HSP90AB1, HSP90AA1 | PTPRC 1389/4885ADORA2A 3575/4885MAPT 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.