Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | ULK1 | O75385 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11593046 | 0.92 | PTGS1 (0.75) | KMT2AMEN1NPC1RAB9APBRM1 | |
| SCHEMBL1352405 | 0.90 | PTGS1 (0.68) | KMT2AMEN1NPC1RAB9APBRM1 | |
| SCHEMBL2127722 | 0.90 | PTGS1 (0.77) | KMT2AMEN1NPC1RAB9APTGS1 | |
| SCHEMBL6866138 | 0.89 | KMT2A (0.78) | KMT2AMEN1NPC1RAB9APTGS1 | |
| SCHEMBL17744815 | 0.87 | KMT2A (0.73) | KMT2AMEN1PTGS1POLBKDM4E | |
| SCHEMBL309467 | 0.87 | PTGS1 (0.72) | KMT2AMEN1PTGS1POLBKDM4E | |
| SCHEMBL31171945 | 0.87 | PTGS1 (0.72) | KMT2AMEN1PTGS1POLBKDM4E | |
| SCHEMBL6153699 | 0.86 | PTGS1 (0.67) | KMT2AMEN1NPC1RAB9APTGS1 | |
| Hydrochloric Acid SCHEMBL6153673 | 0.84 | PTGS1 (0.65) | KMT2AMEN1NPC1RAB9APTGS1 | |
| SCHEMBL6479304 | 0.84 | PGR (0.72) | KMT2AMEN1NPC1RAB9APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | KMT2A 2379/4885MEN1 4038/4885NPC1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.