Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | CDC42 | P60953 | 1/20 | 0.41 |
| ▸ | RAC1 | P63000 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605254 | 0.85 | ACP3 (0.41) | PTGS2PTGS1CYP1A2TSHR | |
| SCHEMBL7607704 | 0.81 | MME (0.44) | — | |
| SCHEMBL27366043 | 0.79 | AKR1C3 (0.49) | AKR1C3AKR1C2TDP1L3MBTL1UGT2B7 | |
| SCHEMBL7645266 | 0.79 | PIN1 (0.42) | AKR1C3AKR1C2GLAUGT2B7CYP1A2 | |
| SCHEMBL7609438 | 0.78 | ACP3 (0.50) | — | |
| SCHEMBL5051241 | 0.77 | PPARG (0.44) | GLAUTS2R | |
| SCHEMBL5059655 | 0.76 | PPARG (0.44) | AKR1C3AKR1C2GLAUGT2B7UTS2R | |
| SCHEMBL8046696 | 0.76 | GLA (0.47) | GLAUGT2B7TSHRUTS2R | |
| SCHEMBL8065556 | 0.75 | PPARG (0.39) | GLAUGT2B7TSHRUTS2R | |
| SCHEMBL5057926 | 0.74 | UGT2B7 (0.43) | AKR1C3AKR1C2GLAUGT2B7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002515040-A | — | — | 2002-05-21 | — | — | JP | claimed |
| EP-0954295-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-10 | — | — | EP | claimed |
| WO-1997048409-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1997-12-24 | — | — | WO | claimed |