Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053330 | 0.81 | FOLH1 (0.42) | PIN1UTS2RPPARGPPARA | |
| SCHEMBL8058470 | 0.80 | ACP3 (0.46) | ALDH1A1 | |
| SCHEMBL5051241 | 0.78 | PPARG (0.44) | GLAPIN1UTS2RMTNR1AMTNR1B | |
| SCHEMBL8065556 | 0.77 | PPARG (0.39) | GLAPIN1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL7606735 | 0.76 | AKR1C3 (0.43) | GLATSHRUTS2RUGT2B7 | |
| SCHEMBL5059655 | 0.75 | PPARG (0.44) | GLAPIN1UTS2RPPARGPPARA | |
| SCHEMBL7645266 | 0.75 | PIN1 (0.42) | GLAPIN1CYP3A4CYP2D6TSHR | |
| SCHEMBL5059819 | 0.73 | PPARG (0.43) | GLAPIN1CYP3A4CYP2D6UTS2R | |
| SCHEMBL5051302 | 0.70 | PPARG (0.56) | PIN1PPARGPPARA | |
| SCHEMBL28374395 | 0.69 | ACP3 (0.42) | CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046180-A | NAALADase inhibitors | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-04 | — | — | US | disclosed |