Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606800 | 0.78 | SLC6A3 (0.37) | SLC6A3SLC6A4ADAM17 | |
| SCHEMBL5409904 | 0.69 | SLC6A3 (0.38) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5407139 | 0.69 | SLC6A3 (0.38) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6359095 | 0.63 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7036780 | 0.63 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6357049 | 0.63 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6357051 | 0.63 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6363204 | 0.63 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7133287 | 0.61 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7133289 | 0.61 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020010207-A1 | Tropane analogs and methods for inhibition of monoamine transport | WILMINGTON TRUST (LONDON) LIMITED, AS SECURITY AGENT (GB) | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010207-A1 | Tropane analogs and methods for inhibition of monoamine transport | SLC6A2, SLC6A4, SLC6A3 | SLC6A3 3/4885SLC6A4 2/4885ADAM17 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.