Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 5/20 | 0.53 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606812 | 1.00 | DPYD (0.53) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL12903446 | 0.75 | DPYD (0.59) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL65892 | 0.75 | DPYD (0.62) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL14405088 | 0.73 | DPYD (0.52) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL190329 | 0.72 | DPYD (0.59) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL190328 | 0.72 | DPYD (0.59) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL27253388 | 0.71 | DPYD (0.55) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL27309856 | 0.71 | DPYD (0.50) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL10795206 | 0.70 | DPYD (0.58) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL2183588 | 0.70 | DPYD (0.53) | DPYDATAD2MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020025296-A1 | Combined use of nucleoside analogues and gene transfection for tissue imaging and therapy | ALBERTA, GOVERNORS OF THE UNIVERSITY OF, THE (CA) | 2002-02-28 | — | — | US | disclosed |
| EP-0784489-A2 | COMPOSITION USE OF NUCLEOSIDE ANALOGUES AND GENE TRANSFECTION FOR TISSUE IMAGING AND THERAPY | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996012508-A2 | COMBINED USE OF NUCLEOSIDE ANALOGUES AND GENE TRANSFECTION FOR TISSUE IMAGING AND THERAPY | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 1996-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020025296-A1 | Combined use of nucleoside analogues and gene transfection for tissue imaging and therapy | SLC29A1, SLC29A2, TK1 | DPYD 1492/4885ATAD2 3493/4885MAPT 4170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.