SCHEMBL65892

SCHEMBL65892

O=c1[nH]cc(C=CBr)c(=O)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DPYD Q12882 5/20 0.62
MAPT P10636 4/20 0.43
ALDH1A1 P00352 2/20 0.43
GAA P10253 2/20 0.43
ATAD2 Q6PL18 1/20 0.43
LMNA P02545 1/20 0.43
CYP19A1 P11511 1/20 0.43
TSHR P16473 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
HTT P42858 1/20 0.43
HBB P68871 1/20 0.43
PMP22 Q01453 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4C Q9H3R0 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL190003 1.00 DPYD (0.62) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL14793573 0.91 DPYD (0.66) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL6512588 0.83 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL933037 0.83 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL5559312 0.82 ATAD2 (0.53) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL5559308 0.82 ATAD2 (0.53) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL8966741 0.79 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL8776005 0.79 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL12903446 0.79 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL190328 0.76 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2072 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
US-10260071-B2 CpG oligonucleotide analogs containing hydrophobic T analogs with enhanced immunostimulatory activity COLEY PHARMACEUTICAL GMBH (DE) 2019-04-16 US claimed
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2017-06-22 US claimed
US-9677067-B2 Compositions and methods for synthetic gene assembly Twist Bioscience Corporation (US) 2017-06-13 US claimed
US-20170159044-A1 COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY Twist Bioscience Corporation 2017-06-08 US claimed
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 US claimed
EP-3157573-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP claimed
EP-3157572-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP claimed
US-20160348115-A1 CpG Oligonucleotide Analogs Containing Hydrophobic T Analogs with Enhanced Immunostimulatory Activity PFIZER INC. 2016-12-01 US claimed
EP-0464511-A2 Process for the preparation of acyclic, substituted nucleosides and its intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-08 EP claimed
EP-0283065-B1 COMBINATIONS OF FU AND BVU AS ANTI-ADENOCARCINOMA AGENTS Stichting REGA V.Z.W. (BE) 1991-05-29 EP claimed
US-4988678-A Fluorouracil and tetrahydrofuryl-5-fluorouracil as an antitumor agent and bromovinyluracil and 5-(2-bromovinyl-2'-deoxyuridine STICHTING REGA VZW (BE) 1991-01-29 US claimed
WO-1990015064-A1 THERAPEUTIC NUCLEOSIDES THE WELLCOME FOUNDATION LIMITED (GB) 1990-12-13 WO claimed
EP-0391411-A2 3'-Substituted methyl nucleosides as antiviral agents Bristol-Myers Squibb Company (US) 1990-10-10 EP claimed
US-4894365-A 5-FLUOROURACIL AND BROMOVINYLURACIL STICHTING REGA VZW (BE) 1990-01-16 US claimed
EP-0283065-A1 Combinations of FU and BVU as anti-adenocarcinoma agents Stichting REGA V.Z.W. (BE) 1988-09-21 EP claimed
EP-0273169-A2 Novel antiviral agents SRI INTERNATIONAL (US) 1988-07-06 EP claimed
EP-0269947-A1 Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1988-06-08 EP claimed
WO-1984004748-A2 NOVEL ANTIVIRAL AGENTS 1984-12-06 WO claimed