Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610419 | 0.86 | KMT2A (0.54) | HIF1AMEN1KMT2AADRA1ACYP2D6 | |
| SCHEMBL7615186 | 0.82 | MAPT (0.49) | MEN1KMT2ACYP2D6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL7608379 | 0.81 | MEN1 (0.37) | HIF1AMEN1KMT2AADRA1ACYP2D6 | |
| SCHEMBL7609912 | 0.81 | GLA (0.50) | MEN1KMT2ALMNAMTNR1AMTNR1B | |
| SCHEMBL7611675 | 0.80 | ADRB2 (0.41) | HIF1ACYP2D6CYP1A2ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL7769570 | 0.80 | HIF1A (0.50) | HIF1AMEN1KMT2AADRA1ACYP2D6 | |
| SCHEMBL7611182 | 0.77 | GAA (0.44) | MEN1KMT2AADRB2ADRB1LMNA | |
| SCHEMBL7041023 | 0.77 | HIF1A (0.61) | HIF1AMEN1KMT2AADRA1ACYP2D6 | |
| SCHEMBL7610435 | 0.76 | ADRB2 (0.52) | MEN1KMT2AADRA1ACYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL7040330 | 0.76 | HIF1A (0.62) | HIF1AMEN1KMT2AADRA1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |