Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615186 | 0.89 | MAPT (0.49) | POLBNPC1RAB9AALDH1A1GAA | |
| SCHEMBL7610407 | 0.88 | GLA (0.48) | GLAPOLBKIF11NPC1RAB9A | |
| SCHEMBL7606867 | 0.81 | HIF1A (0.48) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7612545 | 0.78 | CASR (0.46) | POLBNPC1RAB9AALDH1A1GAA | |
| SCHEMBL7768377 | 0.77 | SMN1; SMN2 (0.48) | NPC1RAB9AALDH1A1GAAMEN1 | |
| SCHEMBL7612159 | 0.76 | RAB9A (0.46) | POLBNPC1RAB9AALDH1A1GAA | |
| SCHEMBL7527009 | 0.75 | ADRB3 (0.48) | GLAPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL7613185 | 0.74 | RAB9A (0.53) | NPC1RAB9AALDH1A1GAAMEN1 | |
| Sulfuric Acid SCHEMBL7540439 | 0.73 | SMN1; SMN2 (0.44) | NPC1RAB9AALDH1A1GAAMEN1 | |
| SCHEMBL7609910 | 0.72 | ADRB1 (0.57) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |