Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15022829 | 0.82 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL10424764 | 0.82 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL1284372 | 0.80 | GPR84 (0.43) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL10586362 | 0.80 | GPR84 (0.43) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL28871111 | 0.77 | GPR84 (0.41) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL6365831 | 0.76 | LMNA (0.38) | GPR84SPHK1FFAR1LMNAMAPT | |
| SCHEMBL28138576 | 0.72 | GPR84 (0.48) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL28237635 | 0.71 | FFAR1 (0.64) | GPR84SPHK1FFAR1LMNAFFAR4 | |
| SCHEMBL11387486 | 0.70 | LMNA (0.41) | GPR84SPHK1FFAR1LMNAMAPT | |
| Hexane SCHEMBL7134957 | 0.69 | TSHR (0.50) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265638-A1 | COMPOSITIONS FOR TRANSDERMAL AND TRANSMUCOSAL ADMINISTRATION OF THERAPEUTIC AGENTS | Pharmaderm Laboratories Ltd. (CA) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001035998-A1 | COMPOSITIONS FOR TRANSDERMAL AND TRANSMUCOSAL ADMINISTRATION OF THERAPEUTIC AGENTS | PHARMADERM LABORATORIES, LTD. (CA) | 2001-05-25 | — | — | WO | disclosed |