Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023359 | 0.91 | DRD1 (0.37) | ROCK2DRD1P2RY1 | |
| SCHEMBL7023357 | 0.91 | DRD1 (0.37) | ROCK2DRD1P2RY1 | |
| SCHEMBL7606996 | 0.85 | MAPK8 (0.34) | ROCK2MAPK8 | |
| SCHEMBL7607004 | 0.81 | DRD1 (0.32) | ROCK2DRD1 | |
| SCHEMBL7019619 | 0.75 | DRD1 (0.35) | ROCK2DRD1P2RY1 | |
| SCHEMBL7019620 | 0.75 | DRD1 (0.35) | ROCK2DRD1P2RY1 | |
| SCHEMBL7019949 | 0.70 | DRD1 (0.34) | DRD1P2RY1 | |
| SCHEMBL7017904 | 0.69 | P2RY1 (0.39) | ROCK2DRD1MAPK8P2RY1 | |
| SCHEMBL7024710 | 0.67 | APLNR (0.43) | DRD1P2RY1 | |
| SCHEMBL7017371 | 0.64 | CYP1A2 (0.41) | DRD1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020161224-A1 | Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them | PULMAN DAVID A (US) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161224-A1 | Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them | HDHD5, DDT, CBR3 | ROCK2 3523/4885DRD1 84/4885MAPK8 3129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.